Zandoná Giovana Paula, Bagatini Lucíola, Woloszyn Natália, de Souza Cardoso Juliane, Hoffmann Jessica Fernanda, Moroni Liziane Schittler, Stefanello Francieli Moro, Junges Alexander, Rombaldi Cesar Valmor
Agroindustrial Science and Technology Department, Federal University of Pelotas, Capão do Leão Campus, s/n, Pelotas, RS 96010-900, Brazil.
Agroindustrial Science and Technology Department, Federal University of Pelotas, Capão do Leão Campus, s/n, Pelotas, RS 96010-900, Brazil; University of Santa Catarina State, BR 282, KM 573, Linha Santa Terezinha, Pinhalzinho, SC 89870-000, Brazil.
Food Res Int. 2020 Nov;137:109573. doi: 10.1016/j.foodres.2020.109573. Epub 2020 Jul 21.
Underexplored species have phytochemical potential for pharmacological and nutraceutical applications. The fruits of such species, including aracá (Psidium cattleianum Sabine), are rich in specialized metabolites with putative antioxidant and antimicrobial activity; therefore, the leaves of these species are also a potential source of bioactive compounds. In this study, araçazeiro leaves were extracted using an aqueous infusion (Al) and a pressurized liquid extraction system with water (PLE-W), ethanol (PLE-E), and 1:1 water:ethanol ratio combination (PLE-W:E). PLE-W:E yielded a greater diversity of extracted compounds. Nonetheless, all extracts showed inhibitory activity against pathogenic Gram-positive and Gram-negative bacteria and antioxidant activity in the in vitro thiobarbituric acid reactive substances (TBARS) and reactive oxygen species (ROS) assays with rat brain and yeast model systems. Thus, araçazeiro leaves can be exploited as a promising source of bioactive compounds.
未被充分研究的物种具有用于药理学和营养保健应用的植物化学潜力。这类物种的果实，包括阿拉卡（番石榴），富含具有假定抗氧化和抗菌活性的特殊代谢产物；因此，这些物种的叶子也是生物活性化合物的潜在来源。在本研究中，使用水浸提法（Al）和分别以水（PLE-W）、乙醇（PLE-E）以及水与乙醇1:1比例组合（PLE-W:E）的加压液体萃取系统对阿拉卡泽罗叶进行提取。PLE-W:E产生了更多样化的提取物。尽管如此，在体外硫代巴比妥酸反应性物质（TBARS）以及使用大鼠脑和酵母模型系统的活性氧（ROS）测定中，所有提取物均显示出对致病性革兰氏阳性和革兰氏阴性细菌的抑制活性以及抗氧化活性。因此，阿拉卡泽罗叶可被开发为一种有前景的生物活性化合物来源。
