Pereira Eliana, Cadavez Vasco, Barros Lillian, Encina-Zelada Christian, Stojković Dejan, Sokovic Marina, Calhelha Ricardo C, Gonzales-Barron Ursula, Ferreira Isabel C F R
Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Food Res Int. 2020 Nov;137:109574. doi: 10.1016/j.foodres.2020.109574. Epub 2020 Jul 20.
The ingestion of bioactive compounds has revealed health benefits, namely in the prevention and/or treatment of several diseases. This work aims to characterize the phenolic profile of three colour varieties of Chenopodium quinoa Willd. grains (black, red and white), and also evaluate their cytotoxic and antimicrobial activity. All varieties revealed the presence of phenolic compounds, namely, quercetin and kaempferol derivatives. In this study, quinoa grains did not reveal any anti-proliferative capacity in tumour cell lines, and, as expected, they were devoid of any toxicity. All of the analysed extracts possessed antibacterial and antifungal activities (inhibitory and bactericidal/fungicidal) against the microbial strains considered, exhibiting promising values of minimum bactericidal concentrations (mean MBC 0.153-0.916 mg/mL) and minimum fungicidal concentrations (mean MFC 0.211-0.884 mg/mL). Quinoa varieties represent a good source of bioactive compounds, interfering beneficially in the organism, specifically as antimicrobial agents. Thus, these extracts could be used in the development of bioactive ingredients.
摄入生物活性化合物已显示出对健康有益，即在预防和/或治疗多种疾病方面。这项工作旨在表征藜麦（Chenopodium quinoa Willd.）三种颜色品种（黑色、红色和白色）籽粒的酚类特征，并评估它们的细胞毒性和抗菌活性。所有品种都含有酚类化合物，即槲皮素和山奈酚衍生物。在本研究中，藜麦籽粒在肿瘤细胞系中未显示出任何抗增殖能力，并且正如预期的那样，它们没有任何毒性。所有分析的提取物对所考虑的微生物菌株均具有抗菌和抗真菌活性（抑制性和杀菌/杀真菌性），表现出有前景的最低杀菌浓度值（平均MBC为0.153 - 0.916毫克/毫升）和最低杀真菌浓度值（平均MFC为0.211 - 0.884毫克/毫升）。藜麦品种是生物活性化合物的良好来源，对生物体有有益影响，特别是作为抗菌剂。因此，这些提取物可用于开发生物活性成分。
