Been Sabrina K, van de Vijver David A M C, Smit Jannigje, Bassant Nadine, Pogány Katalin, Stutterheim Sarah E, Verbon Annelies
Division of Infectious Diseases, Department of Internal Medicine, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
Viroscience Department, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
Diagnostics (Basel). 2020 Nov 20;10(11):980. doi: 10.3390/diagnostics10110980.
We evaluated the feasibility and efficacy of four existing interventions to improve adherence to them in migrants living with HIV (MLWH): directly administered antiretroviral therapy (DAART), group medical appointments (GMA), early detection and treatment of psychological distress, and peer support by trained MLWH. At baseline and after the interventions, socio-demographic characteristics, psychosocial variables, and data on HIV treatment adherence were collected. The two questionnaires were completed by 234/301 (78%) MLWH included at baseline. Detectable HIV RNA decreased (from 10.3 to 6.8%) as did internalized HIV-related stigma (from 15 to 14 points), and self-reported adherence increased (between 5.5 and 8.3%). DAART and GMA were not feasible interventions. Screening of psychological distress was feasible; however, follow-up diagnostic screening and linkage to psychiatric services were not. Peer support for and by MLWH was feasible. Within this small intervention group, results on HIV RNA < 400 copies/mL (decrease of 23.6%) and outpatient clinic attendance (up to 20.4% kept more appointments) were promising.
我们评估了四种现有干预措施在感染艾滋病毒的移民（MLWH）中提高其依从性的可行性和有效性：直接监督下的抗逆转录病毒治疗（DAART）、集体医疗预约（GMA）、心理困扰的早期检测与治疗以及由经过培训的MLWH提供同伴支持。在基线期和干预措施实施后，收集了社会人口学特征、心理社会变量以及艾滋病毒治疗依从性数据。234/301名（78%）纳入基线期的MLWH完成了两份调查问卷。可检测到的艾滋病毒RNA有所下降（从10.3%降至6.8%），内化的与艾滋病毒相关的耻辱感也有所下降（从15分降至14分），自我报告的依从性有所提高（提高了5.5%至8.3%）。DAART和GMA不是可行的干预措施。心理困扰筛查是可行的；然而，后续的诊断筛查以及与精神科服务的联系则不可行。MLWH之间的同伴支持是可行的。在这个小干预组中，艾滋病毒RNA<400拷贝/毫升的结果（下降了23.6%）以及门诊就诊情况（高达20.4%的人预约更多）很有前景。
