Zierold Kristina M, Sears Clara G, Hagemeyer Abby N, Brock Guy N, Polivka Barbara J, Zhang Charlie H, Sears Lonnie
Environmental Health Sciences, School of Public Health, The University of Alabama at Birmingham, Birmingham, Alabama, USA
Epidemiology, Brown University, Providence, Rhode Island, USA.
BMJ Open. 2020 Nov 23;10(11):e038960. doi: 10.1136/bmjopen-2020-038960.
Fly ash is a waste product generated from burning coal for electricity. It is comprised of spherical particles ranging in size from 0.1 µm to over 100 µm in diameter that contain trace levels of heavy metals. Large countries such as China and India generate over 100 million tons per year while smaller countries like Italy and France generate 2 to 3 million tons per year. The USA generates over 36 million tons of ash, making it one of the largest industrial waste streams in the nation. Fly ash is stored in landfills and surface impoundments exposing communities to fugitive dust and heavy metals that leach into the groundwater. Limited information exists on the health impact of exposure to fly ash. This protocol represents the first research to assess children's exposure to coal fly ash and neurobehavioural outcomes.
We measure indoor exposure to fly ash and heavy metals, and neurobehavioural symptoms in children aged 6 to 14 years old. Using air pollution samplers and lift tape samples, we collect particulate matter ≤10 µm that is analysed for fly ash and heavy metals. Toenails and fingernails are collected to assess body burden for 72 chemical elements. Using the Behavioural Assessment and Research System and the Child Behaviour Checklist, we collect information on neurobehavioural outcomes. Data collection began in September 2015 and will continue until February 2021.
This study was approved by the Institutional Review Boards of the University of Louisville (#14.1069) and the University of Alabama at Birmingham (#300003807). We have collected data from 267 children who live within 10 miles of two power plants. Children are at a greater risk for environmental exposure which justifies the rationale for this study. Results of this study will be distributed at conferences, in peer-reviewed journals and to the participants of the study.
粉煤灰是燃煤发电产生的一种废弃物。它由直径从0.1微米到超过100微米的球形颗粒组成,含有微量重金属。中国和印度等大国每年产生超过1亿吨,而意大利和法国等较小的国家每年产生200万至300万吨。美国每年产生超过3600万吨粉煤灰,使其成为该国最大的工业废物流之一。粉煤灰储存在垃圾填埋场和地表蓄水池中,使社区暴露于逸散性粉尘和渗入地下水中的重金属。关于接触粉煤灰对健康影响的信息有限。本方案是评估儿童接触煤粉煤灰及其神经行为结果的首次研究。
我们测量6至14岁儿童室内接触粉煤灰和重金属的情况以及神经行为症状。使用空气污染采样器和升降胶带样本,我们收集直径≤10微米的颗粒物,对其进行粉煤灰和重金属分析。采集儿童的脚趾甲和手指甲以评估72种化学元素的身体负担。使用行为评估与研究系统以及儿童行为清单,我们收集有关神经行为结果的信息。数据收集于2015年9月开始,将持续到2021年2月。
本研究已获得路易斯维尔大学机构审查委员会(#14.1069)和阿拉巴马大学伯明翰分校机构审查委员会(#300003807)的批准。我们从居住在两座发电厂10英里范围内的267名儿童中收集了数据。儿童面临更大的环境暴露风险,这为本研究的合理性提供了依据。本研究结果将在会议上、同行评审期刊上以及向研究参与者公布。