From the Division of PET/CT, Gemini Scans, Vadapalani, Chennai, Tamil Nadu, India.
Clin Nucl Med. 2021 Apr 1;46(4):e190-e192. doi: 10.1097/RLU.0000000000003440.
Image-guided biopsy of prostate with multiparametric MRI is being adopted in the workup of prostate adenocarcinoma (PAC). 68Ga-PSMA PET/CT-guided biopsy has also been shown to be equally sensitive in the evaluation of higher-grade tumors with increased PSMA expression. The sensitivity of 68Ga-PSMA PET/CT, however, reduces with lesser PSMA expression in low-grade PAC. Herein, we demonstrate a case where delayed 68Ga-PSMA PET/CT imaging helped in detecting low-grade PAC in BPH.
多参数 MRI 引导下的前列腺影像引导活检目前被应用于前列腺腺癌(PAC)的检查中。68Ga-PSMA PET/CT 引导下的活检在评估 PSMA 高表达的高级别肿瘤时同样具有敏感性。然而,在 PSMA 低表达的低级别 PAC 中,68Ga-PSMA PET/CT 的敏感性会降低。在此,我们展示了一个病例,其中延迟的 68Ga-PSMA PET/CT 成像有助于检测前列腺增生症(BPH)中的低级别 PAC。