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Improved survival and graft function in ex vivo T-cell depleted haploidentical hematopoietic cell transplantation for primary immunodeficiency.

作者信息

Lum Su Han, Sobh Ali, Carruthers Kay, Nademi Zohreh, Watson Helen, McNaughton Peter, Selvarajah Sabeena, Deyà-Martínez Angela, Abinun Mario, Flood Terry, Cant Andrew, Hambleton Sophie, Gennery Andrew R, Slatter Mary

机构信息

Children's Haematopoietic Stem Cell Transplant Unit, Great North Children's Hospital, Newcastle upon Tyne Hospital NHS Foundation Trust, Newcastle upon Tyne, UK.

Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

Bone Marrow Transplant. 2021 May;56(5):1200-1204. doi: 10.1038/s41409-020-01152-2. Epub 2020 Nov 24.

DOI:10.1038/s41409-020-01152-2
PMID:33235352
Abstract
摘要

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NK cell content does not seem to influence engraftment in ex vivo T cell depleted haploidentical stem cell transplantation.在体外T细胞去除的单倍体同基因干细胞移植中，自然杀伤细胞含量似乎并不影响植入。
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