Canady J, Jamil Z, Wilson J, Bernard L J
J Natl Med Assoc. 1987 Dec;79(12):1281-4.
A retrospective analysis of 70 consecutive patients with a clinical diagnosis of intestinal obstruction from January 1983 to September 1985 was reviewed. Mean age was 62 years. Etiological factors included adhesions 50 percent, malignancy 24 percent, volvulus 12 percent, diverticulitis 7 percent, hernias 4 percent, and radiation enteritis, mesenteric infarction, and perforation of the cecum in the remaining 3 percent. Complications included wound infection 9 percent (n = 6), intra-abdominal sepsis 7 percent (n = 5), and recurrent small bowel obstruction 4 percent (n = 3). Overall mortality was 24 percent (n = 7).Results of the univariant analysis showed no association between the clinical signs of intestinal obstruction, that is, fever, tachycardia, leukocytosis, and local tenderness, and gangrenous bowel. A multiple regression analysis showed, however, that only 14 percent of the variance was able to predict the gangrenous bowel based on clinical signs. In conclusion, the classical signs of intestinal obstruction are poor indicators for compromised bowel, and early surgical intervention will reduce the incidence of ischemic bowel and mortality.
对1983年1月至1985年9月间连续70例临床诊断为肠梗阻的患者进行了回顾性分析。平均年龄为62岁。病因包括粘连(50%)、恶性肿瘤(24%)、肠扭转(12%)、憩室炎(7%)、疝气(4%),其余3%为放射性肠炎、肠系膜梗死和盲肠穿孔。并发症包括伤口感染9%(n = 6)、腹腔内感染7%(n = 5)和复发性小肠梗阻4%(n = 3)。总死亡率为24%(n = 7)。单变量分析结果显示,肠梗阻的临床体征,即发热、心动过速、白细胞增多和局部压痛,与坏疽性肠病之间无关联。然而,多元回归分析显示,仅根据临床体征,只有14%的变异能够预测坏疽性肠病。总之,肠梗阻的经典体征对于判断肠功能受损是较差的指标,早期手术干预将降低缺血性肠病的发生率和死亡率。