Bizer L S, Liebling R W, Delany H M, Gliedman M L
Surgery. 1981 Apr;89(4):407-13.
The clinical presentation, treatment, and results of 405 patients with mechanical small intestinal obstruction admitted to the Montefiore Hospital and North Central Bronx Hospitals were reviewed. The etiology of obstruction was adhesions 74%, malignancy 8.6%, hernia 8.1%, inflammatory bowel disease 5.2%, and miscellaneous causes 4.1%. The overall mortality rate for the series was 6.7%, and the incidence of bowel strangulation was 10.1%. Strangulation occurred in 33.3% of the hernia group, 9.0% of the adhesions group, and 2.8% of the malignancy group. The largest single cause of death was related to malignant disease--12 cases (44.4%). Six deaths (22.2%) were caused by bowel strangulation. Of the patients who received more than 24 hours of nonoperative therapy, 46% had relief of obstruction. There was no statistically significant difference in successful results between patients managed with long tubes compared to patients managed with nasogastric tubes. Conservative therapy for malignant obstruction was not successful in 85% of cases. The presence of bowel strangulation shows a positive correlation with age (greater than 70 years), feculant vomiting, peristaltic sounds, and a white blood cell count higher than 18,000/mm3. It shows no correlation with onset, localization or type of pain, duration of symptoms, temperature, tachycardia, or x-ray findings. The results of the study indicate that accurate criteria for small bowel obstruction therapy have not been clearly defined except in patients with incarcerated hernias. Nonoperative management is successful in a significnt percentage of patients.
回顾了蒙特菲奥里医院和北中布朗克斯医院收治的405例机械性小肠梗阻患者的临床表现、治疗方法及结果。梗阻病因包括粘连占74%、恶性肿瘤占8.6%、疝占8.1%、炎性肠病占5.2%以及其他原因占4.1%。该系列患者的总死亡率为6.7%,肠绞窄发生率为10.1%。绞窄在疝组中的发生率为33.3%,粘连组为9.0%,恶性肿瘤组为2.8%。最大的单一死亡原因与恶性疾病相关——12例(44.4%)。6例死亡(22.2%)由肠绞窄导致。接受超过24小时非手术治疗的患者中,46%梗阻得到缓解。使用长管治疗的患者与使用鼻胃管治疗的患者在成功结果方面无统计学显著差异。85%的恶性梗阻患者保守治疗未成功。肠绞窄的出现与年龄(大于70岁)、粪样呕吐、肠鸣音以及白细胞计数高于18,000/mm³呈正相关。它与疼痛的发作、定位或类型、症状持续时间、体温、心动过速或X线表现无关。研究结果表明,除嵌顿疝患者外,小肠梗阻治疗的准确标准尚未明确界定。非手术治疗在相当比例的患者中取得成功。