Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Jpn J Clin Oncol. 2021 Apr 1;51(4):569-576. doi: 10.1093/jjco/hyaa224.
Falls are related to frailty, which is known as an unfavorable prognosticator of gastric cancer. In this study, we investigated the influence of the fall risk assessment score on short- and long-term prognoses in patients with gastric cancer after gastrectomy.
A total of 430 patients who underwent gastrectomy for gastric cancer were included in this retrospective study. The fall risk assessment score was scored by nursing staffs on admission. We investigated the relationships between the fall risk assessment score and clinicopathological findings, postoperative outcomes and prognoses. We assigned patients with a fall risk assessment score ≥7 to the high-risk group (92 cases, 21.4%) and those with a fall risk assessment score <6 to the low-risk group (338 cases, 78.6%).
There were no significant differences between the two groups in pathological stage of gastric cancer and postoperative complications, but the high-risk group had significantly longer postoperative hospital stays than the low-risk group (P < 0.001). The overall and the relapse-free survival rates in the high-risk group were significantly lower than those in the low-risk group. The high-risk group was one of the independent poor prognostic factors for overall survival, with a hazard ratio of 2.91 (P ≤ 0.001) in univariate analysis and a hazard ratio of 2.74 (P = 0.008) in multivariate analysis.
While the fall risk assessment score is an objective and easy-to-use method to assess fall risk and frailty, it may present a prognostic factor in gastric cancer.
跌倒与衰弱有关,衰弱被认为是胃癌预后不良的指标。本研究旨在探讨胃癌患者胃切除术后跌倒风险评估评分对短期和长期预后的影响。
回顾性分析 430 例行胃切除术治疗的胃癌患者。护理人员在入院时对跌倒风险评估评分进行评分。我们调查了跌倒风险评估评分与临床病理特征、术后结局和预后之间的关系。我们将跌倒风险评估评分≥7 的患者分配到高风险组(92 例,21.4%),评分<6 的患者分配到低风险组(338 例,78.6%)。
两组患者胃癌病理分期和术后并发症无显著差异,但高风险组患者术后住院时间明显长于低风险组(P<0.001)。高风险组的总生存率和无复发生存率明显低于低风险组。高风险组是总生存的独立预后不良因素之一,单因素分析的危险比为 2.91(P≤0.001),多因素分析的危险比为 2.74(P=0.008)。
虽然跌倒风险评估评分是一种客观且易于使用的评估跌倒风险和衰弱的方法,但它可能是胃癌的一个预后因素。