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空气污染与结膜炎患者门诊量的时间序列分析:以中国泰安为例。

Air pollution and hospital outpatient visits for conjunctivitis: a time-series analysis in Tai'an, China.

机构信息

Institute for Environmental and Climate Research, Jinan University, Guangzhou, 511443, China.

Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Guangzhou, 511443, China.

出版信息

Environ Sci Pollut Res Int. 2021 Mar;28(12):15453-15461. doi: 10.1007/s11356-020-11762-4. Epub 2020 Nov 25.

Abstract

Conjunctivitis is one of the most common eye-related health problems and significantly influences patients' quality of life. Whether air pollution increased the risks of conjunctivitis is still unclear. Daily counts of outpatient visits for conjunctivitis, air pollution, and meteorological data during January 1, 2015-December 31, 2019 were collected from Tai'an, China. Generalized additive model with Poisson distribution was used to estimate the relationship between air pollution and visits for conjunctivitis, after controlling for the long-term and seasonal trends, weather variables, and day of the week. The effect of air pollution on visits for conjunctivitis was generally acute and significant at the current day and disappeared after 2 days. The relative risk of conjunctivitis visits associated with per 10 μg/m increases in PM, PM, SO, and NO at lag 0-2 days was 1.006 (95% CI: 1.001-1.011), 1.003 (95% CI: 1.000-1.0107), 1.023 (95% CI: 1.009-1.037), and 1.025 (95% CI: 1.010-1.040), respectively. The impact of air pollution on visits for conjunctivitis varied greatly by individual characteristics. The impact of NO was higher in males than in females, with the opposite trend for SO and PM. Effect estimates of air pollutants were higher among return visits for conjunctivitis, the elderly, and white-collar workers. Our study highlights that the vulnerable subpopulations should pay more attention to protect themselves from air pollution.

摘要

结膜炎是最常见的眼部健康问题之一,严重影响患者的生活质量。空气污染是否会增加结膜炎的风险尚不清楚。本研究收集了 2015 年 1 月 1 日至 2019 年 12 月 31 日期间中国泰安的每日门诊就诊量、空气污染和气象数据。采用泊松分布的广义加性模型,在控制长期和季节性趋势、气象变量和星期几的基础上,估计空气污染与结膜炎就诊次数之间的关系。空气污染对结膜炎就诊的影响通常在当前日急性且显著,2 天后消失。滞后 0-2 天 PM、PM、SO 和 NO 每增加 10 μg/m 时,结膜炎就诊的相对风险分别为 1.006(95%CI:1.001-1.011)、1.003(95%CI:1.000-1.0107)、1.023(95%CI:1.009-1.037)和 1.025(95%CI:1.010-1.040)。空气污染对结膜炎就诊的影响因个体特征而异。与女性相比,男性的 NO 影响更大,而 SO 和 PM 的趋势相反。空气污染对结膜炎复诊、老年人和白领的影响估计值更高。本研究强调,脆弱人群应更加注意保护自己免受空气污染的影响。

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