Deeg K H, Wehner S, Rupprecht T, Singer H
Kardiologische Abteilung, Universität Erlangen-Nürnberg.
Klin Padiatr. 1987 Nov-Dec;199(6):411-23. doi: 10.1055/s-2008-1026832.
15 infants (gestational age 47 +/- 11 weeks; weight 3180 +/- 1082 g) with angiocardiographically proven coarctation of the aorta and 53 healthy infants (gestational age 39 +/- 8 weeks; weight 2830 +/- 1418 g) were investigated by echocardiography and pulsed doppler sonography. In all children pulsed doppler recordings were obtained in the anterior cerebral artery (prestenotic reference vessel) and the truncus coeliacus (poststenotic reference vessel). Nine variables were measured from each doppler signal: The maximal systolic velocity, the endsystolic and enddiastolic velocity, the pulsatility-index, the acceleration slope (peak rate of acceleration), the deceleration slope (peak rate of deceleration), the antegrade flow time and the acceleration and deceleration time. The healthy infants showed a pulsatile flow profile in the anterior cerebral artery and the truncus coeliacus. In normal subjects the maximal systolic velocity and the acceleration slope in the truncus coeliacus were always higher than in the anterior cerebral artery. There was no difference in the endsystolic and enddiastolic velocity, the pulsatility-index, the flow times and the deceleration slope. In children with coarctation of the aorta a decreased and nonpulsatile flow in the truncus coeliacus could be shown. The following variables were significantly lower than in the healthy control group: The maximal systolic velocity, the pulsatility-index, the acceleration and deceleration slope and the antegrade flow time and acceleration time. In the anterior cerebral arteries of children with coarctation the maximal systolic and enddiastolic velocity were significantly higher than in the healthy control group. Pulsed doppler recordings were obtained in 9 patients after surgical correction: The maximal systolic and endsystolic velocity, the pulsatility-index, the acceleration and deceleration slope in the truncus coeliacus increased significantly although these values were lower than in the healthy control group. The flow parameters in the anterior cerebral arteries postoperatively showed no significant difference from the preoperative values. Pulsed dopplersonography of the flow in the anterior cerebral artery and the truncus coeliacus is a good method for diagnosis of coarctation of the aorta and postoperative controls.
对15例经心血管造影证实患有主动脉缩窄的婴儿（胎龄47±11周；体重3180±1082克）和53例健康婴儿（胎龄39±8周；体重2830±1418克）进行了超声心动图和脉冲多普勒超声检查。在所有儿童中，在前脑动脉（缩窄前参考血管）和腹腔干（缩窄后参考血管）进行了脉冲多普勒记录。从每个多普勒信号中测量九个变量：最大收缩期速度、收缩末期和舒张末期速度、搏动指数、加速度斜率（峰值加速度率）、减速度斜率（峰值减速度率）、正向血流时间以及加速和减速时间。健康婴儿在前脑动脉和腹腔干中显示出搏动性血流分布。在正常受试者中，腹腔干中的最大收缩期速度和加速度斜率总是高于前脑动脉。收缩末期和舒张末期速度、搏动指数、血流时间和减速度斜率没有差异。在患有主动脉缩窄的儿童中，可以显示出腹腔干中血流减少且无搏动。以下变量明显低于健康对照组：最大收缩期速度、搏动指数、加速度和减速度斜率以及正向血流时间和加速时间。在患有主动脉缩窄的儿童的前脑动脉中，最大收缩期和舒张末期速度明显高于健康对照组。对9例手术矫正后的患者进行了脉冲多普勒记录：腹腔干中的最大收缩期和收缩末期速度、搏动指数、加速度和减速度斜率显著增加，尽管这些值低于健康对照组。术后前脑动脉的血流参数与术前值无显著差异。前脑动脉和腹腔干血流的脉冲多普勒超声检查是诊断主动脉缩窄和术后复查的良好方法。
