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经肛门微创手术(TAMIS)后的长期肠道功能

Long-Term Bowel Function after Transanal Minimally Invasive Surgery (TAMIS).

作者信息

Goldenshluger Michael, Gutman Yaara, Katz Aviad, Schtrechman Gal, Westrich Gal, Nissan Aviram, Segev Lior

机构信息

Department of General and Oncological Surgery C, Sheba Medical Center, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel.

出版信息

Isr Med Assoc J. 2020 Jul;22(7):426-430.

Abstract

BACKGROUND

Transanal minimally invasive surgery (TAMIS) is a single port access platform used for full thickness local excision of rectal lesions. It is an appealing alternative to a radical resection of rectum that often can cause a significant bowel dysfunction described as low anterior resection syndrome (LARS). LARS is evaluated using a validated score. Functional outcomes of patients undergoing TAMIS has not yet been evaluated using the LARS score.

OBJECTIVES

To evaluate long-term bowel function in patients who underwent TAMIS.

METHODS

In this case series, all patients who underwent TAMIS in a single tertiary institute between 2011 and 2017 were retrospectively reviewed. We evaluated bowel function using the LARS score questionnaire through telephone interviews.

RESULTS

The study consisted of 23 patients, average age of 67 ± 6.98 year; 72% were male. The median follow-up from the time of surgery was 5 years. Six patients (26.08%) had malignant type lesions. The average height of the lesion from the anal verge was 7.4 cm. The average size of the specimen was 4 cm. The total LARS score revealed that 17 patients (73.91%) had no definitive LAR syndrome following the surgery. Four patients (17.39%) fit the description of minor LARS and only two (8.69%) presented with major LARS.

CONCLUSIONS

TAMIS provides relatively good long-term functional outcomes in terms of bowel function. Further randomized studies with larger cohorts are still needed to better evaluate the outcomes.

摘要

背景

经肛门微创手术(TAMIS)是一种用于直肠病变全层局部切除的单孔入路平台。它是直肠根治性切除的一种有吸引力的替代方法,直肠根治性切除常常会导致严重的肠道功能障碍,即低位前切除综合征(LARS)。LARS通过一个经过验证的评分系统进行评估。尚未使用LARS评分系统评估接受TAMIS治疗患者的功能结局。

目的

评估接受TAMIS治疗患者的长期肠道功能。

方法

在这个病例系列研究中,对2011年至2017年期间在一家三级医疗机构接受TAMIS治疗的所有患者进行了回顾性分析。我们通过电话访谈使用LARS评分问卷评估肠道功能。

结果

该研究纳入了23例患者,平均年龄为67±6.98岁;72%为男性。手术时间至随访的中位时间为5年。6例患者(26.08%)患有恶性病变。病变距肛缘的平均高度为7.4 cm。标本的平均大小为4 cm。总的LARS评分显示,17例患者(73.91%)术后没有明确的LAR综合征。4例患者(17.39%)符合轻度LARS的描述,只有2例(8.69%)表现为重度LARS。

结论

就肠道功能而言,TAMIS提供了相对良好的长期功能结局。仍需要进一步开展更大样本量的随机研究,以更好地评估结局。

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