Creutzfeldt W
Abteilung Gastroenterologie und Endokrinologie, Medizinische Universitätsklinik, Göttingen.
Langenbecks Arch Chir. 1987;372:373-8. doi: 10.1007/BF01297848.
Chronic pancreatitis is despite increasing incidence a rare disease. Studies about its natural history are sparse. Undisputed indication for operative intervention are local complications. Intractable pain without such local complications should only seldom be an indication for pancreatic surgery. Since very different surgical procedures are performed in similar anatomical situations randomized prospective studies are needed. The problems of controlled studies in surgery are discussed.
尽管慢性胰腺炎的发病率在上升,但它仍是一种罕见疾病。关于其自然病程的研究很少。手术干预的明确指征是局部并发症。没有此类局部并发症的顽固性疼痛很少应成为胰腺手术的指征。由于在相似的解剖情况下会采用非常不同的手术方法,因此需要进行随机前瞻性研究。文中讨论了外科手术对照研究的问题。