Midodrine administration during critical illness: fixed-dose or titrate to response?
作者信息
Riker Richard R, Gagnon David J
机构信息
Neuroscience Institute and Department of Critical Care Services, Maine Medical Center, Professor of Medicine, Tufts University School of Medicine, 22 Bramhall Street, Portland, ME, 04102, USA.
Clinical Pharmacist, Maine Medical Center, Assistant Professor of Medicine, Faculty Scientist I, Maine Medical Center Research Institute, Tufts University School of Medicine, 22 Bramhall Street, Portland, ME, 04102, USA.
出版信息
Intensive Care Med. 2021 Feb;47(2):249-251. doi: 10.1007/s00134-020-06321-x. Epub 2020 Nov 25.
Abstract
摘要
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Midodrine administration during critical illness: fixed-dose or titrate to response?危重症期间使用米多君：固定剂量还是根据反应滴定？
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Oral Midodrine as an Adjunct in Rapid Weaning of Intravenous Vasopressor Support in Spinal Cord Injury.口服米多君作为脊髓损伤患者快速停用静脉血管升压药支持治疗的辅助用药
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Hemodynamic Effects of an Increased Midodrine Dosing Frequency.增加米多君给药频率的血流动力学效应。
Crit Care Explor. 2021 Apr 26;3(4):e0405. doi: 10.1097/CCE.0000000000000405. eCollection 2021 Apr.
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High-dose midodrine is not effective for treatment of persistent hypotension in the intensive care unit.大剂量米多君对治疗重症监护病房中的持续性低血压无效。
Intensive Care Med. 2021 Feb;47(2):252-253. doi: 10.1007/s00134-020-06333-7. Epub 2021 Jan 8.
本文引用的文献
1
Potential risks in using midodrine for persistent hypotension after cardiac surgery: a comparative cohort study.心脏手术后使用米多君治疗持续性低血压的潜在风险：一项比较队列研究。
Ann Intensive Care. 2020 Sep 14;10(1):121. doi: 10.1186/s13613-020-00737-w.
2
Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS): an international randomised clinical trial.米多君与安慰剂对重症监护病房持续性低血压患者停用血管加压药时间的影响（MIDAS）：一项国际随机临床试验。
Intensive Care Med. 2020 Oct;46(10):1884-1893. doi: 10.1007/s00134-020-06216-x. Epub 2020 Sep 3.
3
Continuation of Newly Initiated Midodrine Therapy After Intensive Care and Hospital Discharge: A Single-Center Retrospective Study.新起点米多君治疗在重症监护和出院后的延续：一项单中心回顾性研究。
Crit Care Med. 2019 Aug;47(8):e648-e653. doi: 10.1097/CCM.0000000000003814.
4
Trends in Use of Midodrine in the ICU: A Single-Center Retrospective Case Series.ICU 中美多君使用趋势：一项单中心回顾性病例系列研究。
Crit Care Med. 2018 Jul;46(7):e628-e633. doi: 10.1097/CCM.0000000000003121.
5
Feasibility, Utility, and Safety of Midodrine During Recovery Phase From Septic Shock.米多君在脓毒性休克复苏期的可行性、实用性和安全性。
Chest. 2016 Jun;149(6):1380-3. doi: 10.1016/j.chest.2016.02.657. Epub 2016 Mar 4.
6
Midodrine for the weaning of vasopressor infusions.用于撤停血管加压药输注的米多君。
J Clin Pharm Ther. 2016 Jun;41(3):260-5. doi: 10.1111/jcpt.12375. Epub 2016 Mar 4.
7
Oral midodrine treatment accelerates the liberation of intensive care unit patients from intravenous vasopressor infusions.口服米多君治疗可加速 ICU 患者停止静脉血管加压素输注。
J Crit Care. 2013 Oct;28(5):756-62. doi: 10.1016/j.jcrc.2013.05.021. Epub 2013 Jul 8.
8
A double-blind, dose-response study of midodrine in neurogenic orthostatic hypotension.米多君治疗神经源性直立性低血压的双盲、剂量反应研究。
Neurology. 1998 Jul;51(1):120-4. doi: 10.1212/wnl.51.1.120.
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