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[糖尿病足综合征 - 第2部分：血运重建、治疗选择、护理结构、复发预防]

[Diabetic foot syndrome-Part 2 : Revascularization, treatment alternatives, care structures, recurrency prophylaxis].

作者信息

Rümenapf G, Morbach S, Rother U, Uhl C, Görtz H, Böckler D, Behrendt C A, Hochlenert D, Engels G, Hohneck A, Sigl M

机构信息

Oberrheinisches Gefäßzentrum Speyer, Diakonissen-Stiftungs-Krankenhaus Speyer, Paul-Egell-Straße 33, 67346, Speyer, Deutschland.

Abteilung Diabetologie und Angiologie, Fachbereich , Innere Medizin, Marienkrankenhaus gGmbH Soest, Soest, Deutschland.

出版信息

Chirurg. 2021 Feb;92(2):173-186. doi: 10.1007/s00104-020-01313-5.

DOI:10.1007/s00104-020-01313-5
PMID:33237367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7875854/
Abstract

Diabetic foot syndrome (DFS) is the most frequent reason for major amputations in Germany. The majority of foot lesions are triggered by repetitive pressure in diabetic polyneuropathy. Peripheral arterial occlusive disease (PAOD) impairs wound healing and is the main risk factor for amputations. The treatment of wounds and infections as well as timely revascularization are decisive. The use of endovascular and vascular surgical methods depends on the distribution pattern and length of the occlusion processes. Both procedures are complementary. Bypass surgery is of great importance for neuroischemic DFS. Multidisciplinary centers that provide revascularization in DFS can achieve an improvement of arterial blood flow in 90% of the cases and reduce the amputation rate by up to 80%. Due to the high recurrence rate of diabetic foot lesions, measures for secondary prophylaxis are of exceptional importance (podological and orthopedic technical care, foot surgery).

摘要

糖尿病足综合征（DFS）是德国进行大截肢手术最常见的原因。大多数足部病变是由糖尿病多发性神经病变中的反复压力引发的。外周动脉闭塞性疾病（PAOD）会损害伤口愈合，是截肢的主要危险因素。伤口和感染的治疗以及及时的血运重建是决定性的。血管内和血管外科方法的使用取决于闭塞过程的分布模式和长度。这两种手术方法相辅相成。旁路手术对神经缺血性DFS非常重要。在DFS中提供血运重建的多学科中心在90%的病例中可实现动脉血流改善，并将截肢率降低多达80%。由于糖尿病足病变的复发率很高，二级预防措施尤为重要（足部护理和矫形技术护理、足部手术）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/9ce288a62729/104_2020_1313_Fig12_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/9ce288a62729/104_2020_1313_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/05e5421f37b3/104_2020_1313_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/4d5eef21195f/104_2020_1313_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/ae7a0eca0ea5/104_2020_1313_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/ee3d082286ee/104_2020_1313_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/3ce795d2ac4d/104_2020_1313_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/f684a0c80961/104_2020_1313_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/5a99e9bad3b6/104_2020_1313_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/b6ca9499173f/104_2020_1313_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/33134810f0f0/104_2020_1313_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/a9e8505f7f17/104_2020_1313_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56a/7875854/9ce288a62729/104_2020_1313_Fig12_HTML.jpg

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本文引用的文献

1
[Diabetic foot syndrome-Part 1 : Definition, pathophysiology, diagnostics and classification].[糖尿病足综合征——第1部分：定义、病理生理学、诊断与分类]
Chirurg. 2021 Jan;92(1):81-94. doi: 10.1007/s00104-020-01301-9.
2
Practical Guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update).《糖尿病足病预防与管理实用指南（IWGDF 2019 更新版）》
Diabetes Metab Res Rev. 2020 Mar;36 Suppl 1:e3266. doi: 10.1002/dmrr.3266.
3
Guidelines on the diagnosis and treatment of foot infection in persons with diabetes (IWGDF 2019 update).
糖尿病足感染的诊断和治疗指南（IWGDF 2019 更新）。
Diabetes Metab Res Rev. 2020 Mar;36 Suppl 1:e3280. doi: 10.1002/dmrr.3280.
4
Outcome of patients with chronic limb-threatening ischemia with and without revascularization.接受和未接受血运重建的慢性肢体威胁性缺血患者的结局。
Vasa. 2020 Mar;49(2):121-127. doi: 10.1024/0301-1526/a000831. Epub 2019 Dec 6.
5
Quality Indicators in Peripheral Arterial Occlusive Disease Treatment: A Systematic Review.外周动脉阻塞性疾病治疗中的质量指标：系统评价。
Eur J Vasc Endovasc Surg. 2019 Nov;58(5):738-745. doi: 10.1016/j.ejvs.2019.06.029. Epub 2019 Sep 13.
6
Determinants of Long-Term Outcomes and Costs in the Management of Critical Limb Ischemia: A Population-Based Cohort Study.关键肢体缺血管理的长期结局和成本的决定因素：一项基于人群的队列研究。
J Am Heart Assoc. 2018 Aug 21;7(16):e009724. doi: 10.1161/JAHA.118.009724.
7
LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial.LeucoPatch 系统治疗英国、丹麦和瑞典的难愈性糖尿病足溃疡：一项观察者设盲、随机对照试验。
Lancet Diabetes Endocrinol. 2018 Nov;6(11):870-878. doi: 10.1016/S2213-8587(18)30240-7. Epub 2018 Sep 19.
8
Lower-extremity amputations in people with and without diabetes in Germany, 2008-2012 - an analysis of more than 30 million inhabitants.2008 - 2012年德国糖尿病患者与非糖尿病患者的下肢截肢情况——对3000多万居民的分析
Clin Epidemiol. 2018 Apr 20;10:475-488. doi: 10.2147/CLEP.S146484. eCollection 2018.
9
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Diabetes Care. 2018 Jul;41(7):1478-1485. doi: 10.2337/dc17-1683. Epub 2018 Apr 16.
10
Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial.蔗糖八硫酸酯敷料与对照敷料治疗神经缺血性糖尿病足溃疡（Explorer）的国际多中心双盲随机对照试验。
Lancet Diabetes Endocrinol. 2018 Mar;6(3):186-196. doi: 10.1016/S2213-8587(17)30438-2. Epub 2017 Dec 20.