Department of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia.
Unit of Biostatistics and Research Methodology, School of Medical Sciences , Universiti Sains Malaysia , Kubang Kerian , 15200 , Kota Bharu , Kelantan , Malaysia.
BMC Pregnancy Childbirth. 2020 Nov 25;20(1):726. doi: 10.1186/s12884-020-03388-8.
Studies on uptake of first dose of intermittent preventive treatment in pregnancy (IPTp) are lacking, despite it being a predictor of subsequent doses. This study aimed at assessing the determinants of uptake of first dose of IPTp among pregnant women at the State Specialist Hospital, Maiduguri.
A cross-sectional study was conducted, in which respondents were selected using a systematic random sampling method, and structured questionnaires were used to obtain information from them. Chi-squared test was used to determine factors associated with uptake of first IPTp dose, while a further multivariate logistic regression was performed to determine its predictors.
Three hundred and eighty respondents answered the survey, whose ages ranged from 15 to 45 years, and 86.8% were multigravid. Sixty five percent of them were aware of IPTp, and 34.7% believed that IPTp could be harmful to their pregnancies. Over a half of the respondents (52.9%) believed that taking all their IPTp medicines was very good for their pregnancies, while 45.0% felt that taking their IPTp medicines was very pleasant. Only two respondents (0.5%) stated that it was very untrue that their significant others thought that they should take all their IPTp medicines. Half of the respondents said it was very easy for them to take all their IPTp medicines even if they were experiencing mild discomforts while taking them. Less than a half (42.37%) had received their first dose of IPTp. In bivariate as well as multivariate analysis, only higher level of knowledge was significantly associated with uptake of first IPTp dose. Those with better knowledge of IPTp were about twice more likely to have taken their first dose of IPTp, compared to those with lower knowledge of IPTp (AOR = 1.85; 95% CI: 1.17-2.92).
Knowledge of IPTp as well as its uptake, were sub-optimal in this study. Since knowledge of IPTp significantly predicts uptake of the first dose of IPTp, there is the need to implement health education campaigns to raise the awareness of pregnant women and their families on the need to receive and comply with it.
尽管首次接受间歇性预防治疗（IPT）是后续剂量的预测指标，但关于孕妇首次接受 IPT 的研究仍然缺乏。本研究旨在评估迈杜古里州立专科医院孕妇首次接受 IPT 的决定因素。
本研究采用横断面研究，通过系统随机抽样方法选择受访者，并使用结构化问卷从他们那里获取信息。卡方检验用于确定与首次 IPT 剂量接受相关的因素，进一步进行多变量逻辑回归以确定其预测因素。
380 名受访者回答了调查，年龄在 15 至 45 岁之间，86.8%是多胎妊娠。其中 65%的人知道 IPT，34.7%的人认为 IPT 对怀孕可能有害。超过一半的受访者（52.9%）认为服用所有 IPT 药物对怀孕非常有益，而 45.0%的人认为服用 IPT 药物非常愉快。只有两名受访者（0.5%）表示，他们的重要他人认为他们应该服用所有 IPT 药物，这是非常不真实的。一半的受访者表示，即使在服用药物时感到轻微不适，他们也很容易服用所有 IPT 药物。只有不到一半（42.37%）的人接受了第一剂 IPT。在单变量和多变量分析中，只有更高的知识水平与首次接受 IPT 剂量显著相关。与知识水平较低的人相比，知识水平较高的人更有可能接受第一剂 IPT（AOR=1.85；95%CI：1.17-2.92）。
本研究中，IPT 的知识水平以及接受程度都不理想。由于 IPT 知识显著预测了首次接受 IPT 的剂量，因此需要开展健康教育活动，提高孕妇及其家属对接受和遵守 IPT 的认识。
