[经皮盲目肝活检在肝外胆管闭锁术前诊断中的价值]
[Value of percutaneous blind liver biopsy in preoperative diagnosis of atresia of the extrahepatic bile ducts].
作者信息
Deutsch J
机构信息
Universitäts-Kinderklinik Graz.
出版信息
Monatsschr Kinderheilkd. 1987 Nov;135(11):763-9.
During a period of 7 years the case histories of 60 infants with direct hyperbilirubinaemia were prospectively evaluated. At presentation the majority of infants had an age below 1 month. By close clinical follow-up of all infants including the observation of acholic stools (21 infants), quantitative estimations of lipoprotein X during cholestyramine therapy (17 infants), cholescintigraphy (20 infants) and percutaneous liver biopsy (17 infants) the efficiency of the preoperative diagnostic work-up reached 96.6%. Liver biopsies were carried out selectively in only 29.3% of all infants (47.6% in infants with acholic stools and 17.9% in infants with normal stools); their efficiency in the differential diagnosis of extrahepatic biliary atresia was 88.2%.
在7年的时间里，对60例直接胆红素血症婴儿的病历进行了前瞻性评估。就诊时，大多数婴儿年龄小于1个月。通过对所有婴儿进行密切的临床随访，包括观察无胆汁粪便（21例婴儿）、考来烯胺治疗期间脂蛋白X的定量测定（17例婴儿）、肝胆闪烁显像（20例婴儿）和经皮肝活检（17例婴儿），术前诊断检查的效率达到了96.6%。仅在所有婴儿中的29.3%（无胆汁粪便婴儿中为47.6%，粪便正常婴儿中为17.9%）中选择性地进行了肝活检；其在肝外胆道闭锁鉴别诊断中的效率为88.2%。
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