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[Kanamycin sulfate--an inducer of recA gene in Escherichia coli].

作者信息

Kiselev V I

出版信息

Mol Gen Mikrobiol Virusol. 1987 Sep(9):41-4.

PMID:3323901
Abstract

Kanamycin sulphate causes the efficient induction of recA gene, being an inhibitor of protein synthesis. Kanamycin is not known to damage the DNA structure. Possibly, the antibiotic ability to induce the SOS-genes is explained by activation of endogenous nucleases activity or by the increase of "alarmone" synthesis, the latter playing the "trigger" role in derepression of SOS-operon.

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