Guo Yixian, Wei Yukui, Teng Lianghong, Lan Xiaoxi, Zhao Hong, Sun Wanling
Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China.
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China.
Curr Probl Cancer. 2021 Jun;45(3):100672. doi: 10.1016/j.currproblcancer.2020.100672. Epub 2020 Nov 19.
Dural plasmacytoma is a type of multiple myeloma of the central nervous system. Our patient presented with symptoms of headache. Imaging findings suspected glioblastoma, whereas pathological findings revealed mucosa-associated lymphoid tissue lymphoma associating with plasma cell differentiation. Further in-depth studies confirmed a diagnosis of dural plasmacytoma. This case indicates that morphological variations may occur in the extramedullary involvement of CD20-positive multiple myeloma. The multidisciplinary team contributes to the diagnosis of hematological diseases.
硬脑膜浆细胞瘤是中枢神经系统多发性骨髓瘤的一种类型。我们的患者表现出头痛症状。影像学检查结果怀疑为胶质母细胞瘤,而病理检查结果显示为黏膜相关淋巴组织淋巴瘤伴浆细胞分化。进一步深入研究确诊为硬脑膜浆细胞瘤。该病例表明,CD20阳性多发性骨髓瘤髓外浸润可能会出现形态学变异。多学科团队有助于血液系统疾病的诊断。