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硬脑膜浆细胞瘤作为多发性骨髓瘤的首发表现:一例病例报告及文献复习

Dural plasmacytoma as the initial presentation of multiple myeloma: A case report and review of the literature.

作者信息

Guo Yixian, Wei Yukui, Teng Lianghong, Lan Xiaoxi, Zhao Hong, Sun Wanling

机构信息

Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China.

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China.

出版信息

Curr Probl Cancer. 2021 Jun;45(3):100672. doi: 10.1016/j.currproblcancer.2020.100672. Epub 2020 Nov 19.

DOI:10.1016/j.currproblcancer.2020.100672
PMID:33239229
Abstract

Dural plasmacytoma is a type of multiple myeloma of the central nervous system. Our patient presented with symptoms of headache. Imaging findings suspected glioblastoma, whereas pathological findings revealed mucosa-associated lymphoid tissue lymphoma associating with plasma cell differentiation. Further in-depth studies confirmed a diagnosis of dural plasmacytoma. This case indicates that morphological variations may occur in the extramedullary involvement of CD20-positive multiple myeloma. The multidisciplinary team contributes to the diagnosis of hematological diseases.

摘要

硬脑膜浆细胞瘤是中枢神经系统多发性骨髓瘤的一种类型。我们的患者表现出头痛症状。影像学检查结果怀疑为胶质母细胞瘤,而病理检查结果显示为黏膜相关淋巴组织淋巴瘤伴浆细胞分化。进一步深入研究确诊为硬脑膜浆细胞瘤。该病例表明,CD20阳性多发性骨髓瘤髓外浸润可能会出现形态学变异。多学科团队有助于血液系统疾病的诊断。

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引用本文的文献

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Brain Circ. 2024 Sep 26;10(3):277-280. doi: 10.4103/bc.bc_101_23. eCollection 2024 Jul-Sep.
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Cancer Med. 2024 Feb;13(4):e7017. doi: 10.1002/cam4.7017.
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Solitary Primary Intracranial Extramedullary Plasmacytoma With Lymph Node Metastasis.
伴有淋巴结转移的孤立性原发性颅内髓外浆细胞瘤。
Cureus. 2022 Apr 2;14(4):e23767. doi: 10.7759/cureus.23767. eCollection 2022 Apr.