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[原发性颅内表皮样癌伴桥小脑角表皮样囊肿——1例报告]

[Primary intracranial epidermoid carcinoma accompanied with epidermoid cyst in the cerebellopontine angle--a case report].

作者信息

Matsuno A, Shibui S, Ochiai C, Inoya H, Takakura K

机构信息

Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Japan.

出版信息

No Shinkei Geka. 1987 Aug;15(8):851-8.

PMID:3323934
Abstract

A case of epidermoid carcinoma arising in an epidermoid cyst in the cerebellopontine angle is presented. Clinical features and CT appearance are discussed in comparison with those of benign epidermoid cyst. A 43-year-old man was admitted to the Department of Neurosurgery, University of Tokyo Hospital on April 14, 1983, with complaints of right facial numbness and weakness of six months' history. On neurological examination, sensation of the right half of the face was decreased in all modalities. Marked atrophy of the ipsilateral temporal muscle was also noted. Right facial paresis of peripheral type was evident. Gag reflex was decreased on the same side. Except for a slightly increased left deep tendon reflexes, there were no pyramidal tract signs. A CT without contrast material failed to show any abnormalities. A postcontrast CT demonstrated an irregular enhancement in the right cerebellopontine angle. The finding of asymmetry of the ambient cistern indicated minimum mass effect on the metrizamide CT cisternography. Suboccipital exploration of the right cerebellopontine angle was carried out on April 28, 1983. Leaving a part of the capsule indenting the pons between the roots of the fifth and the seventh nerve, we removed a white pearly tumor. Histological diagnosis was typical epidermoid cyst. He left the hospital one month later with signs of the right seventh and the eighth nerve. His postoperative course, however, was beyond our expectation. Over a few months following his discharge, left hemiparesis as well as horizontal and vertical nystagmus gradually developed. He was readmitted on November 10, 1983. A postcontrast CT revealed enlargement of the enhanced lesion filling the right ambient cistern.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本文报告1例起源于桥小脑角表皮样囊肿的表皮样癌。将其临床特征和CT表现与良性表皮样囊肿进行了比较。一名43岁男性于1983年4月14日因右面部麻木和无力6个月而入住东京大学医院神经外科。神经系统检查发现,右侧面部所有感觉减退。同侧颞肌明显萎缩。右侧周围性面瘫明显。同侧咽反射减弱。除左侧深腱反射略有增强外,未发现锥体束征。平扫CT未显示任何异常。增强CT显示右侧桥小脑角有不规则强化。环池不对称的表现提示在脑池造影CT上有最小的占位效应。1983年4月28日对右侧桥小脑角进行了枕下探查。在保留部分压迫脑桥的囊壁于第五和第七神经根部之间的情况下,我们切除了一个白色珍珠样肿瘤。组织学诊断为典型的表皮样囊肿。他一个月后出院,遗留右侧第七和第八神经损伤的体征。然而,他的术后病程出乎我们的意料。出院后的几个月里,逐渐出现左侧偏瘫以及水平和垂直眼球震颤。他于1983年11月10日再次入院。增强CT显示填充右侧环池的强化病变增大。(摘要截选至250字)

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