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改良上颌骨摆动入路用于翼腭窝原发性恶性肿瘤切除术

Modified Maxillary-Swing Approach for Resection of Primary Malignancies in the Pterygopalatine Fossa.

作者信息

Xie Li, Huang Wenxiao, Wang Junqi, Zhou Yue, Chen Jie, Chen Xue

机构信息

Department of Head and Neck Surgery, Hunan Cancer Hospital, Xiangya School of Medicine, Central South University, Changsha, China.

Department of Radiation Oncology, Hunan Cancer Hospital, Xiangya School of Medicine, Central South University, Changsha, China.

出版信息

Front Oncol. 2020 Nov 9;10:530381. doi: 10.3389/fonc.2020.530381. eCollection 2020.

Abstract

BACKGROUND

resection of malignancies in the pterygopalatine fossa (PPF) poses critical challenges. Using the modified maxillary-swing (MMS) approach, we achieved monobloc removal of primary malignancies in this region. This study provides a detailed account of the surgical techniques and indications used.

METHODS

We enrolled seven patients with primary malignancies in the PPF during a period from January 2012 to January 2019 in this retrospective study. After malignancies were confirmed by biopsy as well as evaluation with computed tomography (CT) and magnetic resonance imaging (MRI) scans, all of the patients underwent MMS surgery under general anesthesia to extirpate these tumors. We performed regular postoperative follow-up using CT and MRI scans.

RESULTS

resection was successfully performed in all cases. We observed negative margins in six cases and positive margins in one patient with adenoid cystic carcinoma, who received postoperative radiotherapy. The most common complication was facial numbness. During the follow-up period (range, 6-69 months), one patient suffered from recurrence, while the others did not.

CONCLUSION

The advantages of the MMS include a wide surgical field, full exposure, and easy manipulation. We expect this approach to become an alternative to the monobloc resection of malignancies in the PPF that involve the infratemporal fossa, maxillary sinus, nasal cavity, orbit, or oral cavity.

摘要

背景

翼腭窝(PPF)恶性肿瘤的切除面临严峻挑战。我们采用改良上颌骨摆动(MMS)入路,实现了该区域原发性恶性肿瘤的整块切除。本研究详细介绍了所使用的手术技术和适应证。

方法

在这项回顾性研究中,我们纳入了2012年1月至2019年1月期间7例PPF原发性恶性肿瘤患者。经活检以及计算机断层扫描(CT)和磁共振成像(MRI)扫描评估确诊为恶性肿瘤后,所有患者均在全身麻醉下接受MMS手术以切除这些肿瘤。我们使用CT和MRI扫描进行定期术后随访。

结果

所有病例均成功完成切除。6例切缘阴性,1例腺样囊性癌患者切缘阳性,该患者接受了术后放疗。最常见的并发症是面部麻木。在随访期间(范围为6 - 69个月),1例患者复发,其他患者未复发。

结论

MMS的优点包括手术视野开阔、暴露充分和操作简便。我们期望这种方法能够成为PPF中累及颞下窝、上颌窦、鼻腔、眼眶或口腔的恶性肿瘤整块切除的一种替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/7682189/b3b8fd0b424b/fonc-10-530381-g001.jpg

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本文引用的文献

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Endoscopic transnasal approaches to pterygopalatine fossa tumors.经鼻内镜入路治疗翼腭窝肿瘤
Head Neck. 2016 Apr;38 Suppl 1:E214-20. doi: 10.1002/hed.23972. Epub 2015 Jun 16.
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Maxillary swing approach for extended infratemporal fossa tumors.上颌骨摆动入路治疗颞下窝扩展型肿瘤。
Laryngoscope. 2013 Jul;123(7):1607-11. doi: 10.1002/lary.23947. Epub 2013 Mar 27.
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Craniofacial resection for cranial base malignancies involving the infratemporal fossa.颅面切除术治疗累及颞下窝的颅底恶性肿瘤。
Neurosurgery. 2005 Oct;57(4 Suppl):339-47; discussion 339-47. doi: 10.1227/01.neu.0000176648.06547.15.

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