Rehabilitation Research Center, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Science, Tehran, Iran.
National Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain.
Neurol Sci. 2021 Aug;42(8):3233-3239. doi: 10.1007/s10072-020-04941-1. Epub 2020 Nov 26.
Neuropathic pain is a type of pain reported in people with Parkinson's disease. There are various scales to evaluate the characteristics of this kind of pain. The purpose of this study was to investigate the psychometric properties of the Neuropathic Pain Symptom Inventory (NPSI), a specific scale that measures neuropathic pain in Iranian people with Parkinson's disease.
Four hundred forty-seven individuals with Parkinson's disease were recruited in the study. Acceptability, internal consistency (Cronbach's alpha), and test-retest reliability (intraclass correlation coefficient, ICC) of NPSI were calculated. Dimensionality was examined through exploratory factor analysis. For convergent validity, correlations of NPSI with Douleur Neuropathic 4, Brief Pain Inventory, King's Pain Parkinson disease Scale, and Visual Analog Scale-Pain were used. Discriminative validity and sensitivity to change between On- and Off- medication states were analyzed.
A marked floor effect was observed for this scale (64.2%). Cronbach's alpha and ICC were 0.90 and 0.87, respectively. Items of NPSI were placed in 4 factors. A moderate to the strong association (r = 0.55 to 0.85) between NPSI and other scales was obtained. The results of discriminative validity and sensitivity to change indicate the ability of NPSI to show differences between medication states.
The results of this study suggest that NPSI has acceptable reliability, validity, and sensitivity to change, indicating that this scale is suitable for measuring neuropathic pain in Iranian people with Parkinson's disease.
神经性疼痛是帕金森病患者报告的一种疼痛类型。有各种量表可用于评估此类疼痛的特征。本研究旨在调查专门用于评估伊朗帕金森病患者神经性疼痛的神经性疼痛症状量表（NPSI）的心理测量特性。
本研究共纳入 447 名帕金森病患者。计算 NPSI 的可接受性、内部一致性（Cronbach's alpha）和重测信度（组内相关系数 ICC）。通过探索性因子分析检查维度。为了进行收敛效度分析，使用 NPSI 与 Douleur Neuropathic 4、简明疼痛量表、King's 帕金森病疼痛量表和视觉模拟量表疼痛之间的相关性。分析区分效度和药物治疗状态变化的敏感性。
该量表出现明显的地板效应（64.2%）。Cronbach's alpha 和 ICC 分别为 0.90 和 0.87。NPSI 的条目分为 4 个因子。NPSI 与其他量表之间存在中等至较强的关联（r=0.55 至 0.85）。区分效度和变化敏感性的结果表明 NPSI 能够显示药物治疗状态之间的差异。
本研究结果表明，NPSI 具有可接受的信度、效度和变化敏感性，表明该量表适用于评估伊朗帕金森病患者的神经性疼痛。
