National Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience King's College London, London, United Kingdom
Deaprtment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience King's College London, London, United Kingdom.
BMJ Open. 2020 Nov 26;10(11):e043540. doi: 10.1136/bmjopen-2020-043540.
The creation and evaluation of a national record linkage between substance misuse treatment, and inpatient hospitalisation data in England.
A deterministic record linkage using personal identifiers to link the National Drug Treatment Monitoring System (NDTMS) curated by Public Health England (PHE), and Hospital Episode Statistics (HES) Admitted Patient Care curated by National Health Service (NHS) Digital.
Adults accessing substance misuse treatment in England between 1 April 2018 and 31 March 2019 (n=268 251) were linked to inpatient hospitalisation records available since 1 April 1997.
Using a gold-standard subset, linked using NHS number, we report the overall linkage sensitivity and precision. Predictors for linkage error were identified, and inverse probability weighting was used to interrogate any potential impact on the analysis of length of hospital stay.
79.7% (n=213 814) people were linked to at least one HES record, with an estimated overall sensitivity of between 82.5% and 83.3%, and a precision of between 90.3% and 96.4%. Individuals were more likely to link if they were women, white and aged between 46 and 60. Linked individuals were more likely to have an average length of hospital stay ≥5 days if they were men, older, had no fixed residential address or had problematic opioid use. These associations did not change substantially after probability weighting, suggesting they were not affected by bias from linkage error.
Linkage between substance misuse treatment and hospitalisation records offers a powerful new tool to evaluate the impact of treatment on substance related harm in England. While linkage error can produce misleading results, linkage bias appears to have little effect on the association between substance misuse treatment and length of hospital admission. As subsequent analyses are conducted, potential biases associated with the linkage process should be considered in the interpretation of any findings.
创建和评估英国药物滥用治疗与住院数据之间的国家记录链接。
使用个人标识符进行确定性记录链接,以链接由英国公共卫生署(PHE)管理的国家药物治疗监测系统(NDTMS)和由国民保健署(NHS)数字管理的住院患者统计(HES)入院患者护理。
2018 年 4 月 1 日至 2019 年 3 月 31 日期间在英格兰接受药物滥用治疗的成年人(n=268251)与自 1997 年 4 月 1 日以来可获得的住院记录相关联。
使用 NHS 号码进行链接的黄金标准子集,报告了总体链接灵敏度和精度。确定了链接错误的预测因素,并使用逆概率加权来检查对住院时间分析的任何潜在影响。
将药物滥用治疗与住院记录进行链接为评估英格兰治疗对与物质相关的伤害的影响提供了一个强大的新工具。虽然链接错误可能会产生误导性结果,但链接偏差似乎对药物滥用治疗与住院时间之间的关联几乎没有影响。随着后续分析的进行,在解释任何发现时应考虑与链接过程相关的潜在偏差。