Zybina T G
Tsitologiia. 1987 Sep;29(9):1012-9.
Polyploidization peculiarities of tertiary giant trophoblast cells during their active detaching from the ectoplacental cone and migrating into decidua basalis are investigated. On the 12th day of gestation, the ploidy of the majority of cell nuclei varies within 4-8c, although there are a few 16c and 32c nuclei. On the 13th and 14th days of gestation, the ploidy level of tertiary giant trophoblast cells enhances; 8c and 16c nuclei prevail, the percentage of 32c nuclei increases, 64c nuclei arising. The ploidy level of tertiary giant cell coincides with the average and/or maximum ploidy degree of precursor cell populations. The significance of polyploidy as indispensable condition of differentiation of the trophoblast cells that actively invade into maternal tissues is discussed.
研究了三级巨大滋养层细胞在从外胎盘锥体主动脱离并迁移至基底蜕膜过程中的多倍体化特性。在妊娠第12天，大多数细胞核的倍性在4-8c范围内变化，尽管有一些16c和32c的细胞核。在妊娠第13天和第14天，三级巨大滋养层细胞的倍性水平升高；8c和16c的细胞核占主导，32c细胞核的百分比增加，出现了64c的细胞核。三级巨大细胞的倍性水平与前体细胞群体的平均和/或最大倍性程度一致。讨论了多倍体作为积极侵入母体组织的滋养层细胞分化不可或缺条件的意义。
