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一名85岁男性因指甲花所致溶血和急性肾损伤;病例报告

Henna-induced Hemolysis and Acute Kidney Injury in an 85-year-old Man; a Case Report.

作者信息

Asgari Sahel, Esfandbod Mohsen, Haghshomar Maryam

机构信息

Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Email:

Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran. Email:

出版信息

Arch Acad Emerg Med. 2020 Oct 14;8(1):e82. eCollection 2020.

Abstract

Henna is a commonly used traditional cosmetic agent, which also holds medical potentials and is used to treat skin lesions including seborrheic dermatitis or fungal infections and also has possible anti-inflammatory effects. It contains lawsone (2-hydroxy-1,4-naphthoquinone) and, therefore, has the potential to induce oxidative hemolysis. Henna-induced hemolysis has been previously reported in children with Glucose 6-Phosphate Dehydrogenase Deficiency. Here, we report an 85-year-old man who developed hemolytic anemia and acute kidney injury following oral consumption of henna to help his dyspnea. He was treated with hydration, bicarbonate, and dexamethasone. Over the course of hospitalization, the patient developed ventilator-associated pneumonia and was treated with antibiotic. He was discharged after one month. This finding is of high importance due to common use of henna, especially among people with false beliefs regarding traditional and herbal medicine, and highlights the role of a full history taking.

摘要

指甲花是一种常用的传统化妆品原料,它也具有医学潜力,可用于治疗包括脂溢性皮炎或真菌感染在内的皮肤损伤,并且可能具有抗炎作用。它含有指甲花醌(2-羟基-1,4-萘醌),因此有诱导氧化溶血的潜力。先前已有报道称,葡萄糖-6-磷酸脱氢酶缺乏症患儿会出现指甲花诱导的溶血。在此,我们报告一名85岁男性,他口服指甲花以缓解呼吸困难后出现了溶血性贫血和急性肾损伤。他接受了补液、碳酸氢盐和地塞米松治疗。在住院期间,患者发生了呼吸机相关性肺炎,并接受了抗生素治疗。一个月后他出院了。鉴于指甲花的广泛使用,尤其是在那些对传统草药抱有错误观念的人群中,这一发现具有重要意义,并凸显了全面问诊的作用。

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