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干预措施以增加备孕女性对多种维生素的使用:一项 IMPLICIT 网络研究。

Interventions to Increase Multivitamin Use Among Women in the Interconception Period: An IMPLICIT Network Study.

机构信息

Department of Family Medicine and Community Health, University of Pennsylvania, 51 N. 39th Street, Philadelphia, PA, 19104, USA.

Penn Medicine Lancaster General Health Research Institute, Lancaster, PA, USA.

出版信息

Matern Child Health J. 2021 Feb;25(2):207-213. doi: 10.1007/s10995-020-03055-6. Epub 2020 Nov 27.

Abstract

INTRODUCTION

Each year, 3% of infants in the Unites States (US) are born with congenital anomalies, including 3000 with neural tube defects. Multivitamins (MVIs) including folic acid reduce the incidence of these birth defects. Most women do not take recommended levels of folic acid prior to conception or during the interconception period.

METHODS

The Interventions to Minimize Preterm and Low Birth Weight Infants through Continuous Improvement Techniques (IMPLICIT) ICC model was implemented to screen mothers who attend well child visits (WCVs) for their children aged 0-24 months. Mothers were queried for maternal behavioral risks known to affect pregnancy including multivitamin use and use of family planning methods to enhance birth spacing. When appropriate, interventions targeted at those at risk behaviors are offered. A mixed effects logistic regression model was used to calculate the odds ratio (OR) of behavior change in MVI use among mothers who reported not using MVIs.

RESULTS

37.7% of mothers reported not using MVIs at WCVs. 64.0% of mothers received an intervention to improve MVI use in this model. Mothers who received an intervention were more likely to report taking an MVI at the subsequent WCV if they received advice to take MVIs (OR 1.64) or directly received MVI samples (OR 3.09).

CONCLUSIONS

Dedicated maternal counseling during pediatric WCVs is an opportunity to influence behavioral change in women at risk of becoming pregnant. Direct provision of MVIs increases the odds that women will report taking them at a higher rate than provider advice or no counseling at all.

摘要

简介

每年,美国有 3%的婴儿(3000 名患有神经管缺陷)出生时带有先天畸形。多种维生素(MVIs),包括叶酸,可以降低这些出生缺陷的发生率。大多数女性在怀孕前或受孕期间没有服用推荐剂量的叶酸。

方法

通过持续改进技术(IMPLICIT)ICC 模型实施干预措施,以最小化早产儿和低出生体重婴儿的数量。对参加儿童健康访视(WCVs)的 0-24 个月儿童的母亲进行筛查,询问她们是否存在已知会影响妊娠的母亲行为风险,包括使用多种维生素和使用计划生育方法来延长生育间隔。在适当的情况下,会针对那些存在风险行为的人提供干预措施。使用混合效应逻辑回归模型计算在报告未使用多种维生素的母亲中,使用多种维生素的行为改变的优势比(OR)。

结果

37.7%的母亲在 WCV 时报告未使用 MVIs。在这个模型中,64.0%的母亲接受了改善多种维生素使用的干预措施。如果母亲接受了服用多种维生素的建议(OR 1.64)或直接收到了多种维生素样本(OR 3.09),那么她们在随后的 WCV 中更有可能报告正在服用多种维生素。

结论

在儿科 WCV 期间进行专门的孕产妇咨询是影响有怀孕风险的女性行为改变的机会。直接提供多种维生素可以增加女性报告服用多种维生素的比例,高于仅提供建议或不提供咨询的情况。

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