Centre for Energy and Environmental Sustainability, Lucknow 226 029, India.
Centre for Energy and Environmental Sustainability, Lucknow 226 029, India.
Bioresour Technol. 2021 Jan;320(Pt B):124421. doi: 10.1016/j.biortech.2020.124421. Epub 2020 Nov 19.
Recently, microalgal biomass has become an attractive and sustainable feedstock for renewable production of various biochemicals and biofuels. However, attaining required productivity remains a key challenge to develop industrial applications. Fortunately, mixotrophic cultivation strategy (MCS) is leading to higher productivity due to the metabolic ability of some microalgal strain to utilise both photosynthesis and organic carbon compared to phototrophic or heterotrophic processes. The potential of MCS is being explored by researchers for maximized biochemicals and biofuels production however it requires further development yet to reach commercialization stage. In this review, recent developments in the MCS bioprocess for selective value-added (carotenoids) products have been reviewed; synergistic mechanism of carbon and energy was conferred. Moreover, the metabolic regulation of microalgae under MCS for utilized carbon forms and carbon recycling was demonstrated; Additionally, the opportunities and challenges of large-scale MCS have been discussed.
最近，微藻生物质已成为可再生生产各种生化物质和生物燃料的有吸引力和可持续的原料。然而，实现所需的生产力仍然是开发工业应用的关键挑战。幸运的是，混合营养培养策略 (MCS) 通过一些微藻菌株的代谢能力来利用光合作用和有机碳，与光养或异养过程相比，导致更高的生产力。研究人员正在探索 MCS 的潜力，以实现最大化的生化物质和生物燃料生产，但要达到商业化阶段还需要进一步发展。在这篇综述中，回顾了 MCS 生物工艺在选择性增值（类胡萝卜素）产品方面的最新进展；提出了碳和能量的协同作用机制。此外，还证明了 MCS 下微藻对利用碳形式和碳回收的代谢调控；此外，还讨论了大规模 MCS 的机会和挑战。
