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主要治疗患者与转诊治疗患者在治疗手指原发性化脓性关节炎中的对比:一项回顾性对比研究。

Primarily treated patients versus referred patients in the treatment of native septic arthritis of digits: a retrospective comparative study.

机构信息

Department of Orthopaedic Surgery, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.

Department of Orthopaedic Surgery, Inje University Haeundae Paik Hospital, Busan, Republic of Korea.

出版信息

BMC Musculoskelet Disord. 2020 Nov 27;21(1):780. doi: 10.1186/s12891-020-03770-9.

Abstract

BACKGROUND

Septic arthritis of digits needs urgent treatment. When treatments delayed or insufficient, patients may be referred to the upper-level hospital due to uncontrolled infection. We reviewed the treatment history of referred patients and compared the microorganisms and the clinical course of both primary and referred patients as relevant studies are rare.

METHODS

In this retrospective review of consecutive case series, 45 patients (primary, n = 11; referred, n = 34) were treated with multiple irrigation and debridement. Cefazolin was used as empiric antibiotics, then changed according to microbiologic study. Previously used antibiotics, treatment delay, surgical history of the referred patients were reviewed. Identified microorganisms, required surgical intervention, hospital stay, radiologic outcome, functional outcomes were compared between both groups.

RESULTS

In the referred patients, methicillin-resistant Staphylococcus aureus (MRSA) was commonly found and cefazolin was susceptible in only 15% of the cases. Longer hospital stay, prolonged antibiotic therapy, more surgical intervention including flap surgery was required to treat the referred patients. Postoperative pain was not severe in daily activities, but the final range of motion was significantly less in the referred patients compared to the primary patients.

CONCLUSIONS

This study suggests that in the treatment of uncontrolled septic arthritis of the digits, antibiotic agents covering MRSA may shorten the duration of antibiotic therapy in areas of high MRSA incidence. Besides, more number of I & D including flap surgery may be required for the referred patients compared with the primary patients. These findings can help the surgeon in setting up a treatment plan or in counseling of referred patients with uncontrolled septic arthritis of the digits.

摘要

背景

手指化脓性关节炎需要紧急治疗。如果治疗延迟或不充分,由于感染无法控制,患者可能会被转诊至上一级医院。由于相关研究较少,我们回顾了转诊患者的治疗史,并比较了原发性和转诊患者的微生物和临床病程。

方法

在这项连续病例系列的回顾性研究中,对 45 名患者(原发性,n=11;转诊,n=34)进行了多次冲洗和清创术。经验性使用头孢唑林作为抗生素,然后根据微生物学研究进行更改。回顾了转诊患者之前使用的抗生素、治疗延迟、手术史。比较了两组患者的识别微生物、需要手术干预、住院时间、放射学结果、功能结果。

结果

在转诊患者中,耐甲氧西林金黄色葡萄球菌(MRSA)很常见,头孢唑林在 15%的病例中敏感。需要更长的住院时间、延长抗生素治疗、更多的手术干预,包括皮瓣手术,以治疗转诊患者。术后疼痛在日常活动中不严重,但与原发性患者相比,转诊患者的最终活动范围明显较小。

结论

本研究表明,在治疗无法控制的手指化脓性关节炎时,覆盖 MRSA 的抗生素可能会缩短高 MRSA 发生率地区的抗生素治疗时间。此外,与原发性患者相比,转诊患者可能需要更多次数的清创术,包括皮瓣手术。这些发现可以帮助外科医生制定治疗计划或对无法控制的手指化脓性关节炎的转诊患者进行咨询。

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