Lipatov Konstantin V, Asatryan Arthur, Melkonyan George, Kazantcev Aleksandr D, Solov'eva Ekaterina I, Cherkasov Urii E
Department of General Surgery, Institute of Clinical Medicine named after N.V. Sklifosovsky, Sechenov First Moscow State Medical University (Sechenov University), Moscow 119021, Russia.
Wound and Wound Infection Surgery, State Budgetary Institution "City Clinical Hospital named after S.S. Yudin of Moscow Healthcare Department", Moscow 115446, Russia.
World J Orthop. 2022 Jul 18;13(7):622-630. doi: 10.5312/wjo.v13.i7.622.
Septic arthritis of the hand is a serious disease that often results in dysfunction of the joint or even the need to perform amputation of the finger. They rank second in the frequency of occurrence after lesions of the knee joint. Many points concerning the etiology, the timing of the development of cartilage destruction and the development of osteomyelitis, approaches to surgical treatment, the duration of antibiotic therapy, and the start of rehabilitation measures remain the subject of numerous discussions. Based on a search in the PubMed, Web of Science and Google Scholar databases down to 1990-2021, publications on septic arthritis of the hand were found and analyzed. The following inclusion criteria were used in our review: (1) Septic arthritis of the hand; (2) Published in a peer review journal; (3) Written in English; and (4) Full text version available. Studies were excluded if they met any of the following criteria: (1) Letters; (2) Articles published in abstract form only; and (3) Cadaveric studies. Septic arthritis of the hand was characterized by the most frequent damage to the joints of the index and middle fingers (> 50% of cases). Up to 90% of cases, the infection enters the joint as a result of penetrating trauma, animal bites, Staphylococcus aureus became the most frequently isolated microorganism (30%-55%), and its polyantibiotic-resistant form Methicillin-resistant Staphylococcus aureus was found, according to various sources, from 0% to 73% among all isolated Staphylococcus aureus. In arthritis, Pasteurella multocida (6%-11%) is often isolated as a result of animal bites. Articular cartilage destruction in the experiment developed within 24-48 h after infection. In clinical studies, the development of osteomyelitis was noted when treatment was delayed by more than 10 d. X-ray data during the first two weeks were uninformative. Priority of surgical treatment of septic arthritis. Drainage and surgical treatment, and with the development of osteomyelitis, the implementation of arthrodesis. Antibacterial therapy for 2-4 wk and early start of rehabilitation measures. Timely surgical treatment in combination with antibiotic therapy and rehabilitation makes it possible to obtain a positive result in the treatment of septic arthritis of the hand.
手部化脓性关节炎是一种严重疾病,常导致关节功能障碍,甚至需要进行手指截肢。其发病率在膝关节病变之后位居第二。关于病因、软骨破坏及骨髓炎的发展时机、手术治疗方法、抗生素治疗时长以及康复措施的启动等诸多问题,仍是众多讨论的主题。通过在PubMed、科学网和谷歌学术数据库中检索至1990 - 2021年,对手部化脓性关节炎的相关出版物进行了查找和分析。我们的综述采用了以下纳入标准:(1)手部化脓性关节炎;(2)发表于同行评审期刊;(3)英文撰写;(4)有全文版本。若研究符合以下任何一项标准则被排除:(1)信函;(2)仅以摘要形式发表的文章;(3)尸体研究。手部化脓性关节炎的特点是示指和中指关节受损最为常见(>50%的病例)。高达90%的病例中,感染是由穿透性创伤、动物咬伤导致进入关节,金黄色葡萄球菌成为最常分离出的微生物(30% - 55%),根据不同来源,在所有分离出的金黄色葡萄球菌中,其耐多药形式耐甲氧西林金黄色葡萄球菌的占比从0%至73%不等。在关节炎中,多杀巴斯德菌(6% - 11%)常因动物咬伤而被分离出。实验中关节软骨破坏在感染后24 - 48小时内发生。临床研究中,当治疗延迟超过10天时会出现骨髓炎。最初两周的X线数据并无参考价值。手部化脓性关节炎手术治疗的优先事项。引流和手术治疗,若发展为骨髓炎,则实施关节融合术。进行2 - 4周的抗菌治疗并尽早启动康复措施。及时的手术治疗联合抗生素治疗和康复措施能够在手部化脓性关节炎的治疗中取得积极效果。