Department of Internal Medicine, Division of Endocrinology, Weill Cornell Medical College, 1165 York Avenue, New York, NY 10065, USA.
Department of Internal Medicine, Division of Endocrinology, Weill Cornell Medical College, 1165 York Avenue, New York, NY 10065, USA.
Med Clin North Am. 2021 Jan;105(1):149-174. doi: 10.1016/j.mcna.2020.08.018. Epub 2020 Nov 7.
Obesity is a chronic disease caused by dysregulated energy homeostasis pathways that encourage the accumulation of adiposity, which in turn results in the development or exacerbation of weight-related comorbidities. Treatment of obesity relies on a foundation of lifestyle modification; weight loss pharmacotherapy, bariatric surgery and devices are additional tools to help patients achieve their health goals. Appropriate management of patients with obesity provides multiple metabolic benefits beyond weight loss.
肥胖是一种由能量平衡途径失调引起的慢性疾病,它会促使脂肪堆积,从而导致与体重相关的合并症的发展或恶化。肥胖的治疗依赖于生活方式的改变;减肥药物治疗、减重手术和器械是帮助患者实现健康目标的额外工具。肥胖患者的合理管理除了减轻体重之外,还能带来多种代谢益处。