Kirubarajan Abirami, Khan Shawn, Got Tiffany, Yau Matthew, Bryan Jennifer M, Friedman Steven Marc
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
BMJ Open. 2020 Nov 27;10(11):e040547. doi: 10.1136/bmjopen-2020-040547.
To characterise published evidence regarding preclinical and clinical interventions to overcome mask shortages during epidemics and pandemics.
Systematic scoping review.
All healthcare settings relevant to epidemics and pandemics.
English peer-reviewed studies published from January 1995 to June 2020 were included. Literature was identified using four databases (Medline-OVID, EMBASE, CINAHL, Cochrane Library), forwards-and-backwards searching through Scopus and an extensive grey literature search. Assessment of study eligibility, data extraction and evidence appraisal were performed in duplicate by two independent reviewers.
Of the 11 220 database citations, a total of 47 articles were included. These studies encompassed six broad categories of conservation strategies: decontamination, reusability of disposable masks and/or extended wear, layering, reusable respirators, non-traditional replacements or modifications and stockpiled masks. Promising strategies for mask conservation in the context of pandemics and epidemics include use of stockpiled masks, extended wear of disposable masks and decontamination.
There are promising strategies for overcoming face mask shortages during epidemics and pandemics. Further research specific to practical considerations is required before implementation during the COVID-19 pandemic.
对已发表的关于在流行病和大流行期间克服口罩短缺的临床前和临床干预措施的证据进行特征描述。
系统综述。
与流行病和大流行相关的所有医疗环境。
纳入1995年1月至2020年6月发表的英文同行评审研究。使用四个数据库(Medline - OVID、EMBASE、CINAHL、Cochrane图书馆)识别文献,通过Scopus进行前后检索,并进行广泛的灰色文献检索。由两名独立评审员重复进行研究资格评估、数据提取和证据评估。
在11220条数据库引用中,共纳入47篇文章。这些研究涵盖了六大类节约策略:消毒、一次性口罩的可重复使用性和/或延长使用时间、分层、可重复使用的呼吸器、非传统替代品或改良品以及储备口罩(库存口罩)。在大流行和流行病背景下,有前景的口罩节约策略包括使用储备口罩(库存口罩)、延长一次性口罩的使用时间和消毒。
在流行病和大流行期间,有一些有前景的策略来克服口罩短缺。在COVID - 19大流行期间实施之前,需要针对实际考虑因素进行进一步研究。