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欢迎来到新的基因组学:面向口腔医疗专业人员的英国国家医疗服务体系基因组医学服务介绍。

Welcome to the new genomics: an introduction to the NHS Genomic Medicine Service for oral healthcare professionals.

作者信息

Cobourne Martyn T, Irving Melita, Seller Anneke

机构信息

Professor of Orthodontics, Faculty of Dentistry, Oral & Craniofacial Sciences, Centre for Craniofacial Development & Regeneration, King's College London, Floor 27, Guy's Hospital, London, SE1 9RT, UK.

Consultant Clinical Geneticist, Department of Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, Floor 7, Guy's Hospital, London, SE1 9RT, UK.

出版信息

Br Dent J. 2020 Nov;229(10):682-686. doi: 10.1038/s41415-020-2348-2. Epub 2020 Nov 27.

Abstract

Genomic medicine is on the threshold of a significant advance in the United Kingdom (UK) with the introduction of a National Health Service (NHS) Genomic Medicine Service. This world-leading initiative aims to integrate genomic medicine into routine NHS care and has the potential to revolutionise healthcare in the UK, including dentistry. The initial focus will be on increasing diagnostic services for rare diseases and cancer, while also harnessing the use of personalised medicine for therapeutic interventions in multiple disorders. Here, we provide a brief overview of this new service, outlining the historical background that has led to its development and how it will work, as well as discussing some of the wider implications for healthcare within the NHS and highlighting the potential longer-term impact of genomics for oral health.

摘要

随着英国国家医疗服务体系(NHS)基因组医学服务的推出,基因组医学在英国正处于重大进展的开端。这一引领世界的举措旨在将基因组医学融入NHS的常规医疗服务中,并有潜力彻底改变英国的医疗保健,包括牙科。最初的重点将是增加对罕见疾病和癌症的诊断服务,同时利用个性化医疗对多种疾病进行治疗干预。在此,我们简要概述这项新服务,概述导致其发展的历史背景及其运作方式,讨论其对NHS内医疗保健的一些更广泛影响,并强调基因组学对口腔健康的潜在长期影响。

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