Fachler Tahel, Maria Faitataziadou Sofia, Molho-Pessach Vered
Department of Dermatology, Hadassah Medical Center, The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Pediatr Dermatol. 2021 Jan;38(1):334-335. doi: 10.1111/pde.14464. Epub 2020 Nov 28.
Herein we report on a 9-year-old girl with recalcitrant prurigo nodularis unresponsive to multiple standard treatments. She was started on dupilumab therapy with rapid improvement in pruritus within 2 weeks and near complete regression of lesions at 3 months. Dupilumab should be considered as an off-label treatment for refractory prurigo nodularis in children.
在此,我们报告一名9岁女孩,患有顽固性结节性痒疹,对多种标准治疗均无反应。她开始使用度普利尤单抗治疗,2周内瘙痒迅速改善,3个月时皮损几乎完全消退。度普利尤单抗应被视为儿童难治性结节性痒疹的一种非标签治疗方法。