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闭塞疗法提高0.1%他克莫司治疗小儿重度斑秃的疗效：病例报告及文献综述

Occlusive treatment enhances efficacy of tacrolimus 0.1% in a pediatric patient with severe alopecia areata: Case report and literature review.

作者信息

Bimbi César, Kyriakou Georgia, Wollina Uwe

机构信息

Dermatologia Medica & Laser Clinic, Porto Alegre, Brazil.

Department of Dermatology, University General Hospital of Patras, Patras, Greece.

出版信息

Pediatr Dermatol. 2021 Jan;38(1):339-340. doi: 10.1111/pde.14474. Epub 2020 Nov 27.

DOI:10.1111/pde.14474
PMID:33247446
Abstract

Tacrolimus is an immunomodulatory drug, available for topical and systemic treatment of several dermopathies that are characterized by immune dysregulation. In the case of alopecia areata, standard application has proven insufficient to yield satisfactory results. Herein, we present a 6-year-old patient with Down syndrome who was treated with topical tacrolimus 0.1% ointment under occlusion overnight with remarkable clinical improvement within 4 months.

摘要

他克莫司是一种免疫调节药物，可用于局部和全身治疗几种以免疫失调为特征的皮肤病。在斑秃的情况下，已证明标准应用不足以产生令人满意的效果。在此，我们介绍一名6岁的唐氏综合征患者，该患者接受了0.1%他克莫司软膏夜间封包治疗，4个月内临床症状有显著改善。

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Occlusive treatment enhances efficacy of tacrolimus 0.1% in a pediatric patient with severe alopecia areata: Case report and literature review.闭塞疗法提高0.1%他克莫司治疗小儿重度斑秃的疗效：病例报告及文献综述
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