门诊甲状腺切除术治疗甲状腺乳头状癌安全且有益：随机对照试验。
Ambulatory thyroidectomy is safe and beneficial in papillary thyroid carcinoma: Randomized controlled trial.
机构信息
Department of Thyroid Surgery, Xiangya Hospital, Central South University, Changsha, China.
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China.
出版信息
Head Neck. 2021 Apr;43(4):1116-1121. doi: 10.1002/hed.26557. Epub 2020 Nov 28.
BACKGROUND
Currently, no randomized controlled trial has been performed to investigate the safety profiles, economic benefit and mental health of ambulatory thyroidectomy in patients with papillary thyroid carcinoma (PTC).
METHODS
Patients diagnosed with PTC were enrolled in this study and were randomly assigned to ambulatory group and control group. The safety profiles, economic benefit and mental health were investigated.
RESULTS
Four hundred and eleven patients completed the study. There was no significant difference in demographic or tumor index. The incidence of complications was not significantly different (P = .631). The economic cost was significantly lower (P < .001) and hospitalization was significantly shorter (P < .001) in ambulatory group. No significant difference was shown in depression (P = .758) and stress disorder (P = .390). However, the ambulatory group showed a higher point of anxiety (P < .001).
CONCLUSION
The ambulatory thyroidectomy is safe in patients with PTC, with significant benefits of economic cost and hospitalization.
背景
目前，尚无随机对照试验研究探讨门诊甲状腺切除术治疗甲状腺乳头状癌（PTC）患者的安全性、经济效益和心理健康状况。
方法
本研究纳入了诊断为 PTC 的患者，并将其随机分配至门诊组和对照组。调查了安全性、经济效益和心理健康状况。
结果
411 例患者完成了研究。两组在人口统计学或肿瘤指标方面无显著差异。并发症发生率无显著差异（P =.631）。门诊组的经济成本显著降低（P < .001），住院时间显著缩短（P < .001）。抑郁（P =.758）和应激障碍（P =.390）无显著差异。然而，门诊组的焦虑评分更高（P < .001）。
结论
对于 PTC 患者，门诊甲状腺切除术是安全的，具有显著的经济效益和住院时间缩短的优势。
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