Department of Electrical Engineering, Northern Illinois University, EB 340, DeKalb, IL, 60115, USA.
Department of Biochemistry, Northern Illinois University, DeKalb, IL, USA.
Biomed Microdevices. 2020 Nov 27;23(1):1. doi: 10.1007/s10544-020-00537-w.
This paper presents a new approach towards the design of paper based autonomous microfluidic devices. Autonomy in the device operation is achieved through the incorporation of mechanically actuated microfluidic switches that are versatile in their design and may be configured to be simple time triggered ON or OFF switches or more complex switches that can be timed to be in multiple states (timed ON, followed by timed OFF). These switches are self-contained and require no external power for their operation, deriving their functionality solely through stored elastic energy. This paper presents the design and fabrication of these switches as fluidic analogs of electronic transistors, and their integration into microfluidic paper based circuit demonstrating their operation as a programmable paper-based microfluidic device.
本文提出了一种新的方法来设计基于纸张的自主微流控设备。通过结合机械驱动的微流控开关实现设备操作的自主性,这些开关在设计上具有多功能性,可以配置为简单的定时开启或关闭开关,也可以配置为更复杂的开关,可以定时处于多种状态(定时开启,然后定时关闭)。这些开关是自包含的,不需要外部电源来运行,其功能完全来自于存储的弹性能量。本文提出了这些开关的设计和制造方法,将其作为电子晶体管的流体学模拟,并将其集成到基于纸张的微流控电路中,展示了它们作为可编程基于纸张的微流控设备的操作。