从代谢组学中挖掘新型创新性克氏锥虫病治疗方法。
Mining the Metabolome for New and Innovative Chagas Disease Treatments.
机构信息
Texas Children's Hospital Center for Vaccine Development, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Texas Children's Hospital Center for Vaccine Development, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Department of Biology, Baylor University, Waco, TX, USA.
出版信息
Trends Pharmacol Sci. 2021 Jan;42(1):1-3. doi: 10.1016/j.tips.2020.11.007. Epub 2020 Nov 25.
Identifying novel therapeutic targets for Chagas disease is a scientific priority. Recently, Hossain et al. used an innovative metabolomic approach to define disease tolerance mechanisms and identify therapeutic targets for Chagas disease. This is the first study translating metabolomic data to develop novel treatments for Chagas disease.
确定恰加斯病的新治疗靶点是一个科学重点。最近，Hossain 等人采用了一种创新的代谢组学方法来定义疾病耐受机制，并确定恰加斯病的治疗靶点。这是第一项将代谢组学数据转化为开发恰加斯病新疗法的研究。
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