Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
JACC Cardiovasc Imaging. 2021 Mar;14(3):588-598. doi: 10.1016/j.jcmg.2020.08.041. Epub 2020 Nov 25.
This study sought to describe cardiac magnetic resonance (CMR) characteristics of ablation lesions within post-infarction scar.
Chronic ablation lesions created during radiofrequency ablation of ventricular tachycardia (VT) in the setting of prior myocardial infarction have not been described in humans.
Seventeen patients (15 men, ejection fraction 25 ± 8%, 66 ± 6 years of age) with CMR imaging prior to repeat ablation procedures for VT were studied. Electroanatomic maps from first-time procedures and subsequent CMR images were merged and retrospectively compared with electroanatomic maps from repeat procedures.
The delay between the index ablation procedure and the CMR study was 30 ± 29 months. Late gadolinium-enhanced CMR revealed a confluent nonenhancing subendocardial dark core within the infarct-related scar tissue in all patients. Intracardiac thrombi were ruled out by transthoracic and intracardiac echocardiography. These core lesions matched the distribution of prior ablation lesions, and corresponded to unexcitable areas at repeat procedures.
Ablation lesions can be detected by CMR after VT ablation in post-infarction patients and have a different appearance than scar tissue. These lesions can be observed many months after an initial ablation.
本研究旨在描述心肌梗死后瘢痕内消融损伤的心脏磁共振(CMR)特征。
在先前心肌梗死的情况下,射频消融治疗室性心动过速(VT)期间形成的慢性消融损伤在人体中尚未被描述。
17 名患者(15 名男性,射血分数 25 ± 8%,年龄 66 ± 6 岁)在因 VT 进行重复消融程序之前接受了 CMR 成像。首次程序的电解剖图和随后的 CMR 图像被合并,并与重复程序的电解剖图进行回顾性比较。
索引消融程序和 CMR 研究之间的时间间隔为 30 ± 29 个月。所有患者的延迟钆增强 CMR 均显示梗死相关瘢痕组织内存在融合性非增强心内膜暗核。经胸超声心动图和心内超声排除了心内血栓。这些核心病变与先前消融病变的分布相匹配,并与重复程序中的无兴奋区域相对应。
在心肌梗死后患者中,VT 消融后可通过 CMR 检测到消融损伤,其表现与瘢痕组织不同。这些病变可以在初始消融后数月观察到。