Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Fars, Iran.
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Fars, Iran.
Top Companion Anim Med. 2021 Mar;42:100501. doi: 10.1016/j.tcam.2020.100501. Epub 2020 Nov 26.
Ultrasonography is one of the most common methods for the diagnosis of prostate disorders, such as benign prostatic hyperplasia (BPH), in dogs. Changes in the echotexture are one of the indicators used to diagnose prostate disorders. The purpose of this study was to investigate the changes occurred in the dogs' prostate echotexture during the induction of BPH using image analysis. Twenty sexually mature male intact mixed-breed dogs were selected and divided randomly into control and BPH-induced groups. BPH was induced using testosterone and estrogen injections for 63 days. The ultrasound imaging of the dogs' prostate was performed during the induction of BPH on days 0, 21, 42, and 63. The echotexture of the prostate parenchyma was analyzed using the Image J software. Then, the changes in the echotexture and its correlation and linear regression with the prostate volume and canine prostate specific esterase (CPSE) concentration were evaluated by statistical tests. The prostate parenchyma echotexture did not show any significant changes during the induction of BPH and in comparison with that of the control group. While prostate volume and CPSE concentration increased significantly, indicating that BPH was induced in the dogs. There was no significant correlation and linear regression between the prostate echotexture and prostate volume or between the CPSE concentration and prostate echotexture. According to the results, the alteration in the prostate parenchymal echotexture did not occur in the early stages of induced BPH, but significant changes occurred in the prostate volume and CPSE concentration during those early stages.
超声检查是诊断犬前列腺疾病（如良性前列腺增生症，BPH）的最常用方法之一。回声纹理的变化是用于诊断前列腺疾病的指标之一。本研究旨在通过图像分析研究 BPH 诱导过程中犬前列腺回声纹理的变化。选择 20 只性成熟雄性完整杂种犬，随机分为对照组和 BPH 诱导组。使用睾酮和雌激素注射诱导 BPH 63 天。在 BPH 诱导过程中，于第 0、21、42 和 63 天对犬前列腺进行超声成像。使用 Image J 软件分析前列腺实质的回声纹理。然后，通过统计学检验评估回声纹理的变化及其与前列腺体积和犬前列腺特异性酯酶（CPSE）浓度的相关性和线性回归。在 BPH 诱导过程中，前列腺实质回声纹理没有发生任何明显变化，与对照组相比也是如此。虽然前列腺体积和 CPSE 浓度显著增加，但表明犬发生了 BPH。前列腺回声纹理与前列腺体积之间或 CPSE 浓度与前列腺回声纹理之间没有显著相关性和线性回归。根据结果，在诱导的 BPH 早期，前列腺实质回声纹理没有发生改变，但在早期阶段，前列腺体积和 CPSE 浓度发生了显著变化。
