Kutlubaev Mansur Amirovich, Pyykko Ilmari, Hardy Todd A, Gürkov Robert
Department of Neurology, Bashkir State Medical University, Ufa, Russian Federation.
Hearing and Balance Research Unit, Field of Otolaryngology, School of Medicine, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Pract Neurol. 2020 Nov 28. doi: 10.1136/practneurol-2020-002734.
Menière's disease causes paroxysmal rotatory vertigo, due to endolymphatic hydrops, an accumulation of endolymph in the endolymphatic space of the labyrinth. Its major symptoms are attacks of rotatory vertigo lasting minutes to hours, with unilateral hearing loss, tinnitus and aural fullness. As the disease progresses, attacks happen less often, but hearing loss and tinnitus gradually become permanent. Neuro-otological complications may develop, such as benign paroxysmal positional vertigo, vestibular drop attacks and bilateral vestibulopathy. The diagnosis of Menière's disease is based on the typical clinical picture and typical findings on the audiogram. Furthermore, it is now possible to diagnose it by MR of the inner ear. Long-term management has several steps, including diet, diuretics, intratympanic injection of corticosteroid or gentamicin and surgery (endolymphatic sac surgery, grommet insertion, surgical labyrinthectomy).
梅尼埃病会导致阵发性旋转性眩晕,这是由于内淋巴积水,即内淋巴在迷路的内淋巴间隙中积聚所致。其主要症状为持续数分钟至数小时的旋转性眩晕发作,伴有单侧听力损失、耳鸣和耳胀满感。随着疾病进展,发作频率降低,但听力损失和耳鸣会逐渐变为永久性。可能会出现神经耳科并发症,如良性阵发性位置性眩晕、前庭性跌倒发作和双侧前庭病。梅尼埃病的诊断基于典型的临床表现和听力图上的典型表现。此外,现在也可以通过内耳磁共振成像进行诊断。长期管理有多个步骤,包括饮食、利尿剂、鼓室内注射皮质类固醇或庆大霉素以及手术(内淋巴囊手术、鼓膜置管、手术性迷路切除术)。