Santarpia Lidia, Speranza Enza, Santopaolo Maria Laura, Marra Maurizio, Pasanisi Fabrizio
Department of Clinical Medicine and Surgery, Internal Medicine and Clinical Nutrition Unit, Federico II University, Naples, Italy.
J Int Med Res. 2020 Nov;48(11):300060520974229. doi: 10.1177/0300060520974229.
Prolonged vitamin D deficiency may result in lower calcium absorption and osteoporosis, leading to pathologic fractures. We report the case of a young woman with severe, complicated osteoporosis, which developed several years after biliopancreatic diversion that was performed to treat morbid obesity. Chronic low vitamin D levels provided a continuous stimulus for parathormone secretion, which resulted in parathyroid hyperplasia/adenoma and autonomous production of the hormone.
长期维生素D缺乏可能导致钙吸收降低和骨质疏松,进而引发病理性骨折。我们报告了一例年轻女性患有严重、复杂骨质疏松症的病例,该病例在为治疗病态肥胖而进行胆胰转流术后数年出现。慢性低维生素D水平持续刺激甲状旁腺激素分泌,导致甲状旁腺增生/腺瘤以及该激素的自主分泌。