Computer-aided area measurement of ocular images.

Using a combination of computer-aided measurement techniques and fundus camera images, the area of regions of interest on the fundus can be measured. If these area measurements are corrected for the magnification effects of the patient's visual system, and the fundus camera optics, an estimate of the true anatomical size of the measured object can be determined in physical units. While the results of measuring models indicate a maximum error of 6% for the system, the results of clinical trials demonstrate an average error of 10% for well-defined areas of interest, with increasing error of up to 30% for poorly defined areas of interest.