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动态筋膜闭合联合负压伤口闭合及网片介导的筋膜牵引(VAWCM)治疗开放性腹部——一项更新的系统评价

Dynamic Fascial Closure With Vacuum-Assisted Wound Closure and Mesh-Mediated Fascial Traction (VAWCM) Treatment of the Open Abdomen-An Updated Systematic Review.

作者信息

Petersson Patrik, Petersson Ulf

机构信息

Department of Clinical Sciences, Malmö, Faculty of Medicine, Lund University, Lund, Sweden.

Department of Surgery, Skåne University Hospital, Malmö, Sweden.

出版信息

Front Surg. 2020 Nov 5;7:577104. doi: 10.3389/fsurg.2020.577104. eCollection 2020.

Abstract

Several different temporary abdominal closure techniques are described in the context of open abdomen treatment. Techniques based on dynamic fascial closure combined with negative pressure therapy have gained popularity and seem to result in the highest fascial closure rates without increased complications and are highlighted in recent guidelines and recommendations. One dynamic closure technique is the vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) technique, first described in 2007. The aim of this systematic review was to evaluate the VAWCM technique regarding a number of short- and long-term results. A systematic literature search was performed in PubMed, EMBASE, and Cochrane Library databases for articles published between January 1, 2006 and May 8, 2020. The review was independently performed by the two authors according to the PRISMA statements for reporting systematic reviews and meta-analyses. Results were pooled for presentation of weighted means when applicable. A total of 220 articles were screened by title and abstract. Thirty-two articles were assessed for eligibility by full-text review and 15 articles finally remained for review. A total of 600 patients treated with VAWCM were included. The pooled weighted means were as follows: fascial closure, 83.5%; enteroatmospheric fistula, 5.6%; planned ventral hernia, 6.2%; in-hospital survival, 72%; and incisional hernia incidence, 40.5%. Long-term survival ranged between 22 and 72%. Quality of life (SF-36) was reported in two studies showing lower scores than the population mean especially in physical domains. Incisional hernia resulted in lower scores in one but not in the other study. The results of 600 VAWCM-treated patients from 15 studies were evaluated in this systematic review. Earlier findings with high fascial closure rates, low enteroatmospheric fistula, and planned ventral hernia rates as well as high incisional hernia incidences were underlined. Permanent mesh for efficient fascial traction and reinforcement at fascial closure seem to be the next step in evolving an optimal temporary closure technique in open abdomen treatment.

摘要

在开放性腹部治疗的背景下,人们描述了几种不同的临时腹部闭合技术。基于动态筋膜闭合结合负压治疗的技术已受到广泛关注,似乎能实现最高的筋膜闭合率,且不会增加并发症,近期的指南和建议中也着重介绍了这些技术。一种动态闭合技术是真空辅助伤口闭合和网片介导的筋膜牵引(VAWCM)技术,该技术于2007年首次被描述。本系统评价的目的是评估VAWCM技术在一些短期和长期结果方面的情况。在PubMed、EMBASE和Cochrane图书馆数据库中进行了系统的文献检索,以查找2006年1月1日至2020年5月8日期间发表的文章。两位作者根据报告系统评价和荟萃分析的PRISMA声明独立进行了该评价。在适用的情况下,对结果进行汇总以呈现加权平均值。通过标题和摘要共筛选出220篇文章。通过全文审查评估了32篇文章的 eligibility,最终有15篇文章纳入审查。共有600例接受VAWCM治疗的患者被纳入。汇总加权平均值如下:筋膜闭合率为83.5%;肠气瘘为5.6%;计划性腹疝为6.2%;住院生存率为72%;切口疝发生率为40.5%。长期生存率在22%至72%之间。两项研究报告了生活质量(SF - 36),结果显示得分低于总体人群平均水平,尤其是在身体领域。在一项研究中,切口疝导致得分较低,但在另一项研究中并非如此。本系统评价评估了15项研究中600例接受VAWCM治疗患者的结果。强调了早期发现的高筋膜闭合率、低肠气瘘和计划性腹疝发生率以及高切口疝发生率。在开放性腹部治疗中,使用永久性网片进行有效的筋膜牵引和在筋膜闭合时进行加强,似乎是发展最佳临时闭合技术的下一步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7a9/7674165/38bdb50ad10c/fsurg-07-577104-g0001.jpg

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