哌醋甲酯致遗尿：3 例报告。

Methylphenidate-Induced Enuresis: 3 Case Reports.

机构信息

Department of Child and Adolescent Psychiatry, Necmettin Erbakan University Meram School of Medicine.

Department of Child and Adolescent Psychiatry, Dr. Ali Kemal Belviranli Maternity and Children Hospital.

出版信息

Clin Neuropharmacol. 2021;44(1):37-38. doi: 10.1097/WNF.0000000000000422.

DOI:10.1097/WNF.0000000000000422

PMID:33252370

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children and adolescents. Methylphenidate (MPH) is one of the most widely used drugs in the treatment of ADHD. Enuresis can occur comorbidly with ADHD. However, enuresis is sometimes seen in patients with ADHD as an adverse effect of MPH treatment. In contrast, in some cases, MPH reportedly improves enuresis in patients with ADHD comorbid with enuresis. The literature is contradictory with regard to the relationship between MPH and enuresis. This report presents the cases of 3 children with ADHD who displayed enuresis during MPH treatment.

摘要

注意缺陷多动障碍（ADHD）是儿童和青少年中常见的神经发育障碍。哌醋甲酯（MPH）是治疗 ADHD 最广泛使用的药物之一。遗尿症可与 ADHD 共病。然而，遗尿症有时也会出现在 ADHD 患者中，作为 MPH 治疗的不良反应。相比之下，在某些情况下，据报道，MPH 可改善伴有遗尿症的 ADHD 患者的遗尿症。关于 MPH 和遗尿症之间的关系，文献存在矛盾。本报告介绍了 3 例 ADHD 儿童在 MPH 治疗期间出现遗尿症的病例。