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[咽旁间隙肿瘤的影像学表现及治疗选择]

[Imaging of the parapharyngeal space tumors and selection of the treatment].

作者信息

Hou Jiaxin, Wang Ling, Zeng Quan, Wang Xiaoqiang, Wang Zhihai, Hu Guohua

机构信息

Department of Otorhinolaryngology,the First Affiliated Hospital of Chongqing Medical University,Chongqing,400012,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Oct;34(10):937-941. doi: 10.13201/j.issn.2096-7993.2020.10.016.

Abstract

To analyze the imaging features of parapharyngeal space tumors, and to guide the choice of treatment. A retrospective analysis of 75 cases' clinical data of parapharyngeal space tumor was carried out. All patients underwent enhanced CT and/or enhanced MRI, those tumors closely related to blood vessels and vascular tumors were examined by CTA or MRA, those closely related to peripheral nerves were examined by MRN. We evaluated the relationship between tumor and carotid sheath, parotid gland, skull base and hard palate. We choose the treatment according to the imaging features. Imaging revealed 69 benign tumors and 6 malignant tumors. 8 benign tumors chose to follow up, 61 benign tumors and 6 malignant tumors underwent surgery. Among them, 17 cases of tumors were operated by the transoral approach assisted by endoscope, which were located in the medial of carotid sheath, with the main body protruding toward the oropharynx, below the level of the hard palate, and more than 5 mm away from the skull base; 31 cases were resected by the transcervical approach, and the tumor body protruded toward the neck(15 cases were lateral of the carotid sheath, and 16 cases were medial); 16 cases were resected by the transparotid approach, and the tumor harbored a broad interconnecting margin with the parotid gland; there were 3 cases of other approaches(1 case of transnasal approach, 1 case of combined transnasal and transcervical approach, and 1 case of combined transauricular-cervical approach). Postoperative complications occurred in 25 patients, including 9 cases of facial paralysis(6 cases of grade Ⅱ, 2 cases of grade Ⅲ, 1 case of grade Ⅳ), 1 case of facial numbness, 5 cases of Hornor's syndrome; tongue extension deflection in 3 cases, 2 cases cough while drinking water, 1 case of postoperative hematoma formation, 1 case of oral errhysis, hearing loss in 1 case, shoulder shrugging and hand lifting weakness in 1 case, salivary fistula in 1 case, tracheotomy was performed in 1 case because of postoperative oropharyngeal swelling, swallowing obstruction in 1 case, gustatory sweating syndrome in 1 case and acute cerebral infarction was caused by thrombus detachment in 1 case. Imaging results are important basis for the treatment of parapharyngeal space tumors. The choice of surgical approach should be made based on imaging, including the relationship with the big vessels of the neck, the parotid gland, the hard palate, and the distance from the skull base, combined with the nature of the tumor.

摘要

分析咽旁间隙肿瘤的影像学特征,指导治疗方案的选择。对75例咽旁间隙肿瘤患者的临床资料进行回顾性分析。所有患者均行增强CT和/或增强MRI检查,与血管关系密切及血管性肿瘤行CTA或MRA检查,与周围神经关系密切者行MRN检查。评估肿瘤与颈动脉鞘、腮腺、颅底及硬腭的关系。根据影像学特征选择治疗方案。影像学检查显示良性肿瘤69例,恶性肿瘤6例。8例良性肿瘤选择随访,61例良性肿瘤及6例恶性肿瘤行手术治疗。其中,17例肿瘤经口内镜辅助入路手术,肿瘤位于颈动脉鞘内侧,主体突向口咽,位于硬腭水平以下,距颅底5mm以上;31例经颈入路切除,肿瘤主体突向颈部(15例位于颈动脉鞘外侧,16例位于内侧);16例经腮腺入路切除,肿瘤与腮腺有广泛相连边界;另有3例采用其他入路(经鼻入路1例、经鼻联合经颈入路1例、经耳后联合经颈入路1例)。25例患者出现术后并发症,包括面神经麻痹9例(Ⅱ级6例、Ⅲ级2例、Ⅳ级1例)、面部麻木1例、霍纳综合征5例;伸舌偏斜3例、饮水呛咳2例、术后血肿形成1例、口腔渗血1例、听力下降1例、耸肩及抬举上肢无力1例、涎瘘1例、因术后口咽肿胀行气管切开1例、吞咽梗阻1例、味觉出汗综合征1例、血栓脱落致急性脑梗死1例。影像学结果是咽旁间隙肿瘤治疗的重要依据。手术入路的选择应基于影像学表现,包括与颈部大血管、腮腺、硬腭的关系以及距颅底的距离,并结合肿瘤的性质。

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