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本文引用的文献

1
Systemic bevacizumab for recurrent respiratory papillomatosis.全身应用贝伐单抗治疗复发性呼吸道乳头状瘤病。
Int J Pediatr Otorhinolaryngol. 2020 Nov;138:110352. doi: 10.1016/j.ijporl.2020.110352. Epub 2020 Sep 2.
2
Systemic bevacizumab for end-stage juvenile recurrent respiratory papillomas: A case report.全身应用贝伐单抗治疗晚期青少年复发性呼吸道乳头状瘤:一例报告
Int J Pediatr Otorhinolaryngol. 2020 Jan;128:109706. doi: 10.1016/j.ijporl.2019.109706. Epub 2019 Oct 8.
3
[Laryngeal Recurrent Respiratory Papillomatosis: Current Aspects on Diagnosis and Therapy].[喉复发性呼吸道乳头状瘤病:诊断与治疗的现状]
Laryngorhinootologie. 2019 Aug;98(8):577-587. doi: 10.1055/a-0896-9729. Epub 2019 Aug 6.
4
Cost of treating recurrent respiratory papillomavirus in commercially insured and medicaid patients.商业保险和医疗补助患者中复发性呼吸道乳头瘤病毒治疗成本。
Laryngoscope. 2020 May;130(5):1186-1194. doi: 10.1002/lary.28139. Epub 2019 Jun 13.
5
The human papillomavirus vaccine as a treatment for human papillomavirus-related dysplastic and neoplastic conditions: A literature review.人乳头瘤病毒疫苗作为治疗人乳头瘤病毒相关发育异常和肿瘤性疾病的方法:文献综述。
J Am Acad Dermatol. 2020 Jan;82(1):202-212. doi: 10.1016/j.jaad.2019.04.067. Epub 2019 May 11.
6
Update on Recurrent Respiratory Papillomatosis.复发性呼吸道乳头状瘤病的最新进展
Otolaryngol Clin North Am. 2019 Aug;52(4):669-679. doi: 10.1016/j.otc.2019.03.011. Epub 2019 May 8.
7
[Research status of human papillomavirus vaccine for prevention and treatment of respiratory papillomatosis].[人乳头瘤病毒疫苗预防和治疗呼吸道乳头状瘤病的研究现状]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Feb 5;33(2):189-192. doi: 10.13201/j.issn.1001-1781.2019.02.025.
8
Voice improvement in patients with recurrent respiratory papillomatosis after combined treatment with cidofovir and CO laser surgery.复发性呼吸道乳头瘤病患者经更昔洛韦联合 CO2 激光手术后的嗓音改善。
Lasers Med Sci. 2019 Sep;34(7):1433-1440. doi: 10.1007/s10103-019-02735-2. Epub 2019 Feb 14.
9
Implementation of Routine HPV Vaccination in the Management of Recurrent Respiratory Papillomatosis.常规人乳头瘤病毒疫苗接种在复发性呼吸道乳头状瘤病管理中的应用
Ann Otol Rhinol Laryngol. 2019 Apr;128(4):309-315. doi: 10.1177/0003489418821695. Epub 2018 Dec 29.
10
Safe use of systemic bevacizumab for respiratory recurrent papillomatosis in two children.两名儿童中全身使用贝伐单抗治疗复发性呼吸道乳头状瘤病的安全性
Laryngoscope. 2019 Apr;129(4):1001-1004. doi: 10.1002/lary.27674. Epub 2018 Dec 26.

[复发性呼吸道乳头状瘤病辅助治疗的研究进展]

[Research progress in the adjunct therapy of recurrent respiratory papillomatosis].

作者信息

Shen Mengya, Xiao Yang, Ma Lijing, Wang Jun

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Dec;34(12):1145-1148. doi: 10.13201/j.issn.2096-7993.2020.12.022.

DOI:10.13201/j.issn.2096-7993.2020.12.022
PMID:33254355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10127790/
Abstract

Recurrent respiratory papillomatosis (RRP) is a benign tumor of the respiratory tract caused by human papillomavirus (HPV) infection. At present, there is no cure for this disease, and mainly depends on surgical resection to relieve symptoms but cannot prevent recurrence. Multiple surgeries will bring heavy mental and economic burdens to patients and their families. Therefore, researchers are constantly seeking new treatments to reduce the number of operations and prevent recurrence. Hence, research on adjuvant therapy drugs has also been widely carried out, including bevacizumab, cidofovir, HPV vaccine, and Chinese medicine as an adjuvant drug according some reports. This article reviews the adjuvant treatment of RRP in recent years.

摘要

复发性呼吸道乳头状瘤病(RRP)是一种由人乳头瘤病毒(HPV)感染引起的呼吸道良性肿瘤。目前,这种疾病无法治愈,主要依靠手术切除来缓解症状,但无法预防复发。多次手术会给患者及其家庭带来沉重的精神和经济负担。因此,研究人员一直在寻找新的治疗方法以减少手术次数并预防复发。于是,针对辅助治疗药物的研究也广泛开展,据一些报道,包括贝伐单抗、西多福韦、HPV疫苗以及中药作为辅助药物。本文综述了近年来RRP的辅助治疗情况。