Zamora A, Lefranc J P, Salet-Lizee D, Foulques H, Blondon J
Service Chirurgical et Gynécologique, Hôpital de la Salpêtrière, Paris.
J Chir (Paris). 1987 Dec;124(12):672-6.
Data from a series of 58 patients admitted with pyosalpinx, and representing 17.3% of cases of upper genital infections, were used to provide detailed information on therapy. Diagnosis was confirmed by celioscopy or laparotomy in all cases, and treatment essentially multiple antibiotic therapy by parenteral administration of wide spectrum compounds. Three subgroups of patients were distinguished: group 1 (15 cases) received immediate surgery due to severity of clinical picture or doubt as to diagnosis: in 54% the treatment was radical (hysterectomy-castration); group II (26 cases) received medical treatment only; group III (17 cases) underwent surgery after failure of medical treatment; operation was conservative in 52% of cases. Failure of medical treatment was related to a pyosalpinx volume of 8 cm3 or more in 86% of cases. No patient needed recovery surgery, while 3 had long term complications. Microbial flora was mainly anaerobic, diagnosis being dependent of celioscopy findings. Medical treatment alone allowed young women desiring pregnancy to conserve their genital apparatus in 44.8% of cases. When there is a lack of response to treatment, incomplete regression or recurrence then only surgery can be curative: the uterus and ovarian parenchyma should be conserved as far as possible because of new therapeutic perspectives.
选取了58例输卵管积脓患者的数据,这些患者占上生殖道感染病例的17.3%,用于提供详细的治疗信息。所有病例均通过腹腔镜检查或剖腹手术确诊,治疗主要采用经胃肠外给予广谱化合物的多种抗生素疗法。区分出三个亚组患者:第1组(15例)因临床表现严重或诊断存疑而立即接受手术:54%的患者接受了根治性治疗(子宫切除-卵巢切除);第II组(26例)仅接受药物治疗;第III组(17例)在药物治疗失败后接受手术;52%的病例手术为保守性手术。86%的病例中,药物治疗失败与输卵管积脓体积达8立方厘米或更大有关。没有患者需要进行修复手术,有3例出现长期并发症。微生物菌群主要为厌氧菌,诊断取决于腹腔镜检查结果。单纯药物治疗使44.8%希望怀孕的年轻女性保留了生殖器官。当治疗无反应、不完全消退或复发时,只有手术才能治愈:鉴于新的治疗前景,应尽可能保留子宫和卵巢实质。