Corrado Bruno, Ciardi Gianluca, Lucignano Laura
Department of Public Health, Federico II University of Naples, Via S. Pansini 5, 80131 Naples, Italy.
Neurol Int. 2020 Nov 24;12(3):77-88. doi: 10.3390/neurolint12030015.
to find the most up-to-date evidence of the effectiveness and safety of supervised physical therapy in polymyositis/dermatomyositis patients.
a systematic review of the literature in the main scientific databases was carried out. We searched for randomized controlled trials concerning supervised physical therapy and polymyositis/dermatomyositis. The PICOS method was used for the formulation of the clinical query. Methodological quality and the level of evidence of the included studies were assessed using the modified Jadad scale and the Oxford Centre for Evidence-Based Medicine Levels of Evidence guide, respectively.
a total of 2591 articles were found. By applying the inclusion/exclusion criteria, six randomized controlled clinical trials were admitted to the final phase of the review. The compared approaches concerned supervised exercise programs based on strategies of muscle strengthening or aerobic work. Following these exercises, an increase in the maximum rate of oxygen consumption, a decrease in creatine phosphokinase levels, an enhancement in the patient's aerobic performance and an improvement in the quality of life indexes were registered. The methodological quality of the included studies ranged from 3 to 4.5. All the studies were classified as presenting an evidence level of 2b.
supervised physical therapy in polymyositis/dermatomyositis is an effective, safe and free-of-contraindications tool to be used both in the acute and in the established phases of the pathology. However, further and higher-quality studies are necessary to confirm those findings, to clarify the timing of exercise delivery and to guide the choice towards different types of muscle contraction exercises.
寻找关于在多发性肌炎/皮肌炎患者中进行监督下物理治疗的有效性和安全性的最新证据。
对主要科学数据库中的文献进行系统综述。我们搜索了有关监督下物理治疗和多发性肌炎/皮肌炎的随机对照试验。采用PICOS方法制定临床问题。分别使用改良的Jadad量表和牛津循证医学中心证据水平指南评估纳入研究的方法学质量和证据水平。
共找到2591篇文章。通过应用纳入/排除标准，6项随机对照临床试验进入综述的最后阶段。比较的方法涉及基于肌肉强化或有氧运动策略的监督运动计划。进行这些运动后，记录到最大耗氧率增加、肌酸磷酸激酶水平降低、患者有氧运动能力增强以及生活质量指数改善。纳入研究的方法学质量在3至4.5之间。所有研究均被归类为证据水平为2b。
在多发性肌炎/皮肌炎中，监督下物理治疗是一种有效、安全且无禁忌证的工具，可用于疾病的急性期和稳定期。然而，需要进一步的高质量研究来证实这些发现，阐明运动实施的时机，并指导对不同类型肌肉收缩运动的选择。
