Pulmonary and Critical Care Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA
Biomedical Informatics, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
BMJ Case Rep. 2020 Nov 30;13(11):e236231. doi: 10.1136/bcr-2020-236231.
A 71-year-old man was referred to pulmonary clinic for incidental findings of hypermetabolic lung nodule and mediastinal adenopathy on CT FDG PET performed for evaluation of cough. The patient underwent bronchoscopy with endobronchial ultrasound that was non-diagnostic. The patient was subsequently sent for video-assisted thoracoscopic lymph node biopsy notable for confluent caseating granulomas due to chronic infection by Review of previous PDG PET was notable for the flip flop fungus sign-a PDG PET finding that could have altered the patients' clinical course by potentially avoiding the need for invasive surgical tissue diagnosis.
一位 71 岁男性因咳嗽接受 CT FDG PET 检查时偶然发现肺部高代谢结节和纵隔淋巴结肿大,故转至呼吸内科就诊。支气管镜检查和支气管内超声检查均无明确诊断。随后,患者接受了电视辅助胸腔镜下淋巴结活检,活检结果为融合性干酪样肉芽肿,提示慢性感染。回顾患者之前的 PDG PET 检查,发现了“翻转真菌”征象——这一 PDG PET 发现可能通过避免对患者进行有创性手术组织诊断,从而改变其临床病程。