Shao Qiuji, Li Qiang, Wu Qiaowei, Li Tianxiao, Li Li, Chang Kaitao
Department of Cerebrovascular Disease, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan University People's Hospital, Zhengzhou, China.
Department of Radiology, Department of Cerebrovascular Disease, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan University People's Hospital, Zhengzhou, China.
Br J Radiol. 2021 Feb 1;94(1118):20190950. doi: 10.1259/bjr.20190950. Epub 2020 Dec 1.
In-stent restenosis (ISR) after stenting for intracranial stenosis is a significant issue. This study aimed to evaluate the usefulness of the 3D T1-SPACE technique in the follow-up of patients after stent implantation.
Fifteen patients with intracranial arterial stenosis were prospectively enrolled 6-8 months after stenting. Digital subtraction angiography (DSA) and 3D T1-SPACE imaging were performed to evaluate the degree of stenosis and the enhancement of the vessel wall. Bland-Altman plots were used to assess the agreement between the two imaging methods, and the Pearson correlation coefficient was calculated as a measure of the linear correlation.
Eight Enterprise stents and seven Wingspan stents were used in 15 patients. The follow-up DSA after 6-8 months showed that the degree of stenosis was 40% (range, 30-72%), and ISR occurred in 4 of 15 (26.7%) lesions. The degree of stenosis assessed using the 3D T1-SPACE imaging technique was 35% (range, 30-75%). All four patients with ISR demonstrated significant enhancement. The Pearson correlation coefficient between the two methods was 0.959 ( < 0.05), and the Bland-Altman plot showed that all data points were within the consistency limits ([Formula: see text] ± 1.96 s).
As a non-invasive imaging modality, 3D T1-SPACE showed great consistency with DSA in measuring the degree of stenosis after intracranial stenting. It may be used as an optional method for detecting ISR.
This study evaluated the usefulness of 3D T1-SPACE technique in the follow-up of patients after stent implantation, which could be used as an optional and non-invasive method in detection of in-stent restenosis.
颅内狭窄支架置入术后的支架内再狭窄（ISR）是一个重要问题。本研究旨在评估三维T1加权可变翻转角快速自旋回波（3D T1-SPACE）技术在支架植入术后患者随访中的应用价值。
前瞻性纳入15例颅内动脉狭窄患者，于支架置入术后6 - 8个月进行研究。采用数字减影血管造影（DSA）和3D T1-SPACE成像评估狭窄程度及血管壁强化情况。采用Bland-Altman图评估两种成像方法之间的一致性，并计算Pearson相关系数以衡量线性相关性。
15例患者共使用了8枚Enterprise支架和7枚Wingspan支架。6 - 8个月后的随访DSA显示，狭窄程度为40%（范围30% - 72%），15个病变中有4个（26.7%）发生ISR。采用3D T1-SPACE成像技术评估的狭窄程度为35%（范围30% - 75%）。所有4例ISR患者均表现出明显强化。两种方法之间的Pearson相关系数为0.959（P < 0.05），Bland-Altman图显示所有数据点均在一致性界限内（[公式：见原文] ± 1.96s）。
作为一种非侵入性成像方式，3D T1-SPACE在测量颅内支架置入术后的狭窄程度方面与DSA具有高度一致性。它可作为检测ISR的一种可选方法。
本研究评估了3D T1-SPACE技术在支架植入术后患者随访中的应用价值，该技术可作为检测支架内再狭窄的一种可选的非侵入性方法。
